Implantable cardioverter–defibrillators

JP DiMarco - New England Journal of Medicine, 2003 - Mass Medical Soc
Most people do not survive out-of-hospital cardiac arrest, and those who do may have
substantial long-term cognitive and motor impairment. ICDs may avert such events. This …

Atrial fibrillation and congestive heart failure: specific considerations at the intersection of two common and important cardiac disease sets

JR Ehrlich, S Nattel… - Journal of cardiovascular …, 2002 - Wiley Online Library
AF in Congestive Heart Failure. Atrial fibrillation (AF) and congestive heart failure (CHF) are
two increasingly common cardiac disorders with a growing prevalence in the overall …

Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization–induced triggered activity

A Burashnikov, C Antzelevitch - Circulation, 2003 - Am Heart Assoc
Background—Atrial fibrillation (AF) at times recurs immediately after termination of the
arrhythmia. The mechanism (s) responsible for the extrasystole that reinduces AF is largely …

Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes

BO Bingen, MC Engels, MJ Schalij… - Cardiovascular …, 2014 - academic.oup.com
Aims Atrial fibrillation (AF) is the most common cardiac arrhythmia and often involves
reentrant electrical activation (eg spiral waves). Drug therapy for AF can have serious side …

Frequency domain algorithm for quantifying atrial fibrillation organization to increase defibrillation efficacy

TH Everett, LC Kok, RH Vaughn… - IEEE Transactions …, 2001 - ieeexplore.ieee.org
The authors hypothesized that frequency domain analysis of an interatrial atrial fibrillation
(AF) electrogram would show a correlation of the variance of the signal and the amplitude of …

Clinical significance of elevated levels of cardiac troponin T in patients with chronic heart failure.

K Setsuta, Y Seino, N Takahashi, T Ogawa… - The American journal …, 1999 - europepmc.org
Cardiac troponin T, measured by second-generation assay, is a highly sensitive and specific
marker of minor myocardial damage. Cardiac troponin T was elevated in patients with …

Light transmittance in human atrial tissue and transthoracic illumination in rats support translatability of optogenetic cardioversion of atrial fibrillation

ECA Nyns, V Portero, S Deng, T **… - Journal of Internal …, 2023 - Wiley Online Library
Background Optogenetics could offer a solution to the current lack of an ambulatory method
for the rapid automated cardioversion of atrial fibrillation (AF), but key translational aspects …

Multifunctional flexible biointerfaces for simultaneous colocalized optophysiology and electrophysiology

SN Obaid, RT Yin, J Tian, Z Chen… - Advanced Functional …, 2020 - Wiley Online Library
Recent developments in optophysiology techniques such as optogenetics have
revolutionized the ability to actuate cell activity. Further combining optophysiology and …

An automated hybrid bioelectronic system for autogenous restoration of sinus rhythm in atrial fibrillation

ECA Nyns, RH Poelma, L Volkers, JJ Plomp… - Science translational …, 2019 - science.org
Because of suboptimal therapeutic strategies, restoration of sinus rhythm in symptomatic
atrial fibrillation (AF) often requires in-hospital delivery of high-voltage shocks, thereby …

Late‐phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation

A Burashnikov, C Antzelevitch - Pacing and clinical …, 2006 - Wiley Online Library
Early (EAD) and delayed (DAD) afterdepolarizations‐induced triggered activity is capable of
initiating and maintaining cardiac arrhythmias. EAD‐induced triggered responses are …