Predicting recovery in patients with mild traumatic brain injury and a normal CT using serum biomarkers and diffusion tensor imaging (CENTER-TBI): an observational …
Background Even patients with normal computed tomography (CT) head imaging may
experience persistent symptoms for months to years after mild traumatic brain injury (mTBI) …
experience persistent symptoms for months to years after mild traumatic brain injury (mTBI) …
mTBI Biological Biomarkers as Predictors of Postconcussion Syndrome
E Stępniewska, M Kałas, J Świderska, M Siemiński - Brain sciences, 2024 - mdpi.com
Postconcussion syndrome (PCS) is one of the leading complications that may appear in
patients after mild head trauma. Every day, thousands of people, regardless of age, gender …
patients after mild head trauma. Every day, thousands of people, regardless of age, gender …
Maximizing the clinical value of blood-based biomarkers for mild traumatic brain injury
SH Rauchman, A Pinkhasov, S Gulkarov… - Diagnostics, 2023 - mdpi.com
Mild traumatic brain injury (TBI) and concussion can have serious consequences that
develop over time with unpredictable levels of recovery. Millions of concussions occur …
develop over time with unpredictable levels of recovery. Millions of concussions occur …
Association of blood-based biomarkers and 6-month patient-reported outcomes in patients with mild TBI: a CENTER-TBI analysis
Background and Objectives There is seemingly contradictory evidence concerning
relationships between day-of-injury biomarkers and outcomes after mild traumatic brain …
relationships between day-of-injury biomarkers and outcomes after mild traumatic brain …
Genetic vulnerability and adverse mental health outcomes following mild traumatic brain injury: a meta-analysis of CENTER-TBI and TRACK-TBI cohorts
Background Post-traumatic stress disorder (PTSD) and depression are common after mild
traumatic brain injury (mTBI), but their biological drivers are uncertain. We therefore …
traumatic brain injury (mTBI), but their biological drivers are uncertain. We therefore …
Inhibition of mannan-binding lectin associated serine protease (MASP)-2 reduces the cognitive deficits in a mouse model of severe traumatic brain injury
D Mercurio, F Pischiutta, S Seminara, F Tribuzio… - Journal of …, 2024 - Springer
The lectin pathway (LP) of complement mediates inflammatory processes linked to tissue
damage and loss of function following traumatic brain injury (TBI). LP activation triggers a …
damage and loss of function following traumatic brain injury (TBI). LP activation triggers a …
Outcomes after Traumatic Brain Injury with and Without Computed Tomography
Our recent improved understanding of traumatic brain injury (TBI) comes largely from cohort
studies of TBI patients with indication for computed tomography (CT). Using CT head as an …
studies of TBI patients with indication for computed tomography (CT). Using CT head as an …
External Validation of the Post-Concussion Symptoms Rule for Predicting Mild Traumatic Brain Injury Outcome
Persistent symptoms are common after a mild traumatic brain injury (mTBI). The Post-
Concussion Symptoms (PoCS) Rule is a newly developed clinical decision rule for the …
Concussion Symptoms (PoCS) Rule is a newly developed clinical decision rule for the …
Post-concussion symptom burden and dynamics: Insights from a digital health intervention and machine learning
R Blundell, C d'Offay, C Hand, D Tadmor… - PLOS Digital …, 2025 - journals.plos.org
Individuals who sustain a concussion can experience a range of symptoms which can
significantly impact their quality of life and functional outcome. This study aims to understand …
significantly impact their quality of life and functional outcome. This study aims to understand …
Longitudinal changes in sodium concentration and in clinical outcome in mild traumatic brain injury
Ionic imbalances and sodium channel dysfunction, well-known sequelae of traumatic brain
injury (TBI), promote functional impairment in affected subjects. Therefore, non-invasive …
injury (TBI), promote functional impairment in affected subjects. Therefore, non-invasive …