The healing of bone fractures is a well-orchestrated physiological process involving multiple
cell types and signaling molecules interacting at the fracture site to replace and repair bone …

A wide variety of biomaterials have been developed as both stabilizing structures for the
injured bone and inducers of bone neoformation. They differ in chemical composition …

Background Bone defects after trauma, infection, or tumour resection present a challenge for
patients and clinicians. To date, autologous bone graft (ABG) is the gold standard for bone …

So far, how to achieve the optimal regenerative repair of large load-bearing bone defects
using artificial bone grafts is a huge challenge in clinic. In this study, a strategy of combining …

The present study aims to collect data, compare results and assess techniques used for
improving corrosion resistance and mechanical properties of biodegradable Mg alloys for …

Silk fibroin (SF) from Bombyx mori is a promising natural material for the synthesis of
biocompatible and biodegradable hydrogels for use in biomedical applications from tissue …

Tissue engineering is a promising alternative to autografts or allografts for the regeneration
of large bone defects. Cell-free biomaterials with different degrees of sophistication can be …

Critical-size trabecular bone defects remain challenging to treat in orthopedic clinical
practice. This study utilized a polyethylene glycol dispersion method to uniformly disperse …

Understanding the molecular events that regulate osteoblast differentiation is essential for
the development of effective approaches to bone regeneration. In this study, we analysed …

To understand the potential and limitations of the different available surgical techniques
used to treat large, long-bone diaphyseal defects by focusing on union, complication, re …