The heat tolerance of corals is largely determined by their microbial photosymbionts
(Symbiodiniaceae, colloquially known as zooxanthellae). Therefore, manipulating symbiont …

Metabolic gene clusters (MGCs) have provided some of the earliest glimpses at the
biochemical machinery of yeast and filamentous fungi. MGCs encode diverse genetic …

Spontaneous mutations are the source of new genetic variation and are thus central to the
evolutionary process. In molecular evolution and quantitative genetics, the nature of genetic …

All adaptive alleles in existence today began as mutations, but a common view in ecology,
evolution, and genetics is that non-neutral mutations are much more likely to be deleterious …

Mutations are the main origin of the biodiversity and biological innovations across the tree of
life. The number of mutations in a population depends of the mutation rate, noted μ, a key …

In this chapter, we present the use of Chlamydomonas reinhardtii in experiments designed
to study the evolutionary impacts of whole genome duplication. We shortly introduce the …

Mutations create novel genetic variants, but their contribution to variation in fitness and other
phenotypes may depend on environmental conditions. Furthermore, natural environments …

Although all genetic variation ultimately stems from mutations, their properties are difficult to
study directly. Here, we used multiple mutation accumulation (MA) lines derived from five …

Estimates of the fitness effects of spontaneous mutations are important for understanding the
adaptive potential of species. Here, we present the results of mutation accumulation …

Understanding the origin, maintenance and distribution of nature's astonishing diversity of
reproductive systems is a major endeavour in evolutionary biology. One of the oldest …