We have not yet reached a point at which routine sequencing of large numbers of whole
eukaryotic genomes is feasible, and so it is often necessary to select genomic regions of …

Understanding the relationship between genetic variation and biological function on a
genomic scale is expected to provide fundamental new insights into the biology, evolution …

We have produced a draft sequence of the rice genome for the most widely cultivated
subspecies in China, Oryza sativa L. ssp. indica, by whole-genome shotgun sequencing …

Given the explosive development of new molecular marker techniques over the last decade,
newcomers and experts alike in the field of DNA fingerprinting will find an easy-to-follow …

Metabolic profiling using gas chromatography–mass spectrometry technologies is a
technique whose potential in the field of functional genomics is largely untapped. To …

Single nucleotide polymorphisms (SNPs) represent the most widespread type of sequence
variation in genomes, yet they have only emerged recently as valuable genetic markers for …

During the last few decades, the use of molecular markers, revealing polymorphism at the
DNA level, has been playing an increasing part in plant biotechnology and their genetics …

Map-based cloning is an iterative approach that identifies the underlying genetic cause of a
mutant phenotype. The major strength of this approach is the ability to tap into a nearly …

Denaturing high‐performance liquid chromatography (DHPLC) compares two or more
chromosomes as a mixture of denatured and reannealed PCR amplicons, revealing the …

Positional (or map-based) cloning techniques are widely used to identify the protein
products of genes defined by mutation. In Arabidopsis the information generated by the …