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Outer membrane proteins of pathogenic spirochetes
Pathogenic spirochetes are the causative agents of several important diseases including
syphilis, Lyme disease, leptospirosis, swine dysentery, periodontal disease and some forms …
syphilis, Lyme disease, leptospirosis, swine dysentery, periodontal disease and some forms …
Leptospirosis: pathogenesis, immunity, and diagnosis
RUM Palaniappan, S Ramanujam… - Current opinion in …, 2007 - journals.lww.com
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Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis
Leptospira biflexa is a free-living saprophytic spirochete present in aquatic environments.
We determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira …
We determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira …
Lipoprotein computational prediction in spirochaetal genomes
Lipoproteins are of great interest in understanding the molecular pathogenesis of
spirochaetes. Because spirochaete lipobox sequences exhibit more plasticity than those of …
spirochaetes. Because spirochaete lipobox sequences exhibit more plasticity than those of …
Surfaceome of Leptospira spp
PA Cullen, X Xu, J Matsunaga, Y Sanchez… - Infection and …, 2005 - journals.asm.org
The identification of the subset of outer membrane proteins exposed on the surface of a
bacterial cell (the surfaceome) is critical to understanding the interactions of bacteria with …
bacterial cell (the surfaceome) is critical to understanding the interactions of bacteria with …
Molecular evolution and mosaicism of leptospiral outer membrane proteins involves horizontal DNA transfer
Leptospires belong to a genus of parasitic bacterial spirochetes that have adapted to a
broad range of mammalian hosts. Mechanisms of leptospiral molecular evolution were …
broad range of mammalian hosts. Mechanisms of leptospiral molecular evolution were …
Leptospirosis vaccines
Leptospirosis is a serious infection disease caused by pathogenic strains of the Leptospira
spirochetes, which affects not only humans but also animals. It has long been expected to …
spirochetes, which affects not only humans but also animals. It has long been expected to …
Characterization of the Outer Membrane Proteome of Leptospira interrogans Expressed during Acute Lethal Infection
Pathogenic Leptospira species adapt to a wide range of environmental conditions during
disease transmission and infection. While the proteome of in vitro cultivated Leptospira has …
disease transmission and infection. While the proteome of in vitro cultivated Leptospira has …
Evaluation of Leptospira interrogans knockdown mutants for LipL32, LipL41, LipL21, and OmpL1 proteins
Introduction Leptospirosis is a worldwide zoonosis caused by pathogenic and virulent
species of the genus Leptospira, whose pathophysiology and virulence factors remain …
species of the genus Leptospira, whose pathophysiology and virulence factors remain …
Recombinant vaccines against leptospirosis
Leptospirosis is an important neglected infectious disease that occurs in urban
environments, as well as in rural regions worldwide. Rodents, the principal reservoir hosts of …
environments, as well as in rural regions worldwide. Rodents, the principal reservoir hosts of …