[HTML][HTML] Endocytosis: the nanoparticle and submicron nanocompounds gateway into the cell

D Manzanares, V Ceña - Pharmaceutics, 2020 - mdpi.com
Nanoparticles (NPs) and submicron particles are increasingly used as carriers for delivering
therapeutic compounds to cells. Their entry into the cell represents the initial step in this …

The biophysicochemical interactions at the interfaces between nanoparticles and aquatic organisms: adsorption and internalization

S Ma, D Lin - Environmental Science: Processes & Impacts, 2013 - pubs.rsc.org
Nano–bio interfacial interactions that can likely regulate the potential toxicity of
nanoparticles (NPs) toward aquatic organisms are receiving increasing research interest …

Distinction between active and passive targeting of nanoparticles dictate their overall therapeutic efficacy

TD Clemons, R Singh, A Sorolla, N Chaudhari… - Langmuir, 2018 - ACS Publications
The role of nanoparticles in cancer medicine is vast with debate still surrounding the
distinction between therapeutic efficacy of actively targeted nanoparticles versus passively …

Engineering of cascade-responsive nanoplatform to inhibit lactate efflux for enhanced tumor chemo-immunotherapy

K Li, C Lin, Y He, L Lu, K Xu, B Tao, Z **a, R Zeng… - ACS …, 2020 - ACS Publications
As an increased product of high-rate aerobic glycolysis in tumors, lactate could regulate the
immunosuppressive tumor microenvironment (TME). A PEG-CDM surface modified, GSH …

Polycation-mediated transfection: Mechanisms of internalization and intracellular trafficking

BD Monnery - Biomacromolecules, 2021 - ACS Publications
Polyplex-mediated gene transfection is now in its' fourth decade of serious research, but the
promise of polyplex-mediated gene therapy has yet to fully materialize. Only approximately …

Covalent grafting interface engineering to prepare highly efficient and stable polypropylene/mesoporous SiO2 separator for Li-ion batteries

X Qi, Z Zhang, C Tu, C Zhu, J Wei, Z Yang - Applied Surface Science, 2021 - Elsevier
Due to the deficiency of low melting point and poor wettability of commercial polyolefin
separators, the design and development of ceramic coating separators have been received …

Intrinsic mitochondrial reactive oxygen species (ROS) activate the in situ synthesis of trimethine cyanines in cancer cells

H Heng, G Song, X Cai, J Sun, K Du… - Angewandte …, 2022 - Wiley Online Library
Environment‐responsive in situ synthesis of molecular fluorescent dyes is challenging.
Herein, we develop a photoextension strategy to make trimethine cyanines with decent …

Nanotechnology-driven cell-based therapies in regenerative medicine

D Alzate-Correa, WR Lawrence, A Salazar-Puerta… - The AAPS journal, 2022 - Springer
The administration of cells as therapeutic agents has emerged as a novel approach to
complement the use of small molecule drugs and other biologics for the treatment of …

pH-responsive and charge shielded cationic micelle of poly (L-histidine)-block-short branched PEI for acidic cancer treatment

J Hu, S Miura, K Na, YH Bae - Journal of Controlled Release, 2013 - Elsevier
To address cancer cell heterogeneity while endowing tumor specificity, the approach of
charge shielding/deshielding was tested in vitro and in vivo with a paclitaxel loaded cationic …

[HTML][HTML] Tailoring iron oxide nanoparticles for efficient cellular internalization and endosomal escape

L Rueda-Gensini, J Cifuentes, MC Castellanos… - Nanomaterials, 2020 - mdpi.com
Iron oxide nanoparticles (IONs) have been widely explored for biomedical applications due
to their high biocompatibility, surface-coating versatility, and superparamagnetic properties …