Osteosarcoma is the most common primary malignant bone tumour in children and
adolescents. Due to micrometastatic spread, radical surgery alone rarely results in cure …

Osteosarcoma is the most common primary bone tumour in children and adolescents and
advanced osteosarcoma patients with evidence of metastasis share a poor prognosis …

Osteosarcoma (OS) is the most common type of primary solid tumor that develops in bone.
Although standard chemotherapy has significantly improved long‐term survival over the past …

Simple Summary Osteosarcoma (OS), the most common primary bone tumor, mainly affects
children and adolescents. Unfortunately, in some cases, the absence of response to …

Osteosarcoma is a disease with many complex genetic abnormalities but few well defined
genetic drivers of tumor initiation and evolution. The disease is diagnosed and defined …

Due to the emergence of adjuvant and neoadjuvant chemotherapy, the survival rate has
been greatly improved in osteosarcoma (OS) patients with localized disease. However, this …

Cancer stem cell theory postulates that a small population of tumor-initiating cells is
responsible for the development, progression and recurrence of several malignancies …

Osteosarcoma is the most common type of bone cancer, especially in children and young
adults. The primary treatment for osteosarcoma is a combination of surgery and …

Cancer stem cells (CSC) have a central role in driving tumor growth. Since metabolism is
becoming an important diagnostic and therapeutic target, characterization of CSC line …

Osteosarcoma (OS) is one of the most prevalent malignant cancers with lower survival and
poor overall prognosis mainly in children and adolescents. Identifying the molecular …