A promising frontier: targeting NETs for stroke treatment breakthroughs

H Fang, Y Bo, Z Hao, G Mang, J **, H Wang - Cell Communication and …, 2024 - Springer
Stroke is a prevalent global acute cerebrovascular condition, with ischaemic stroke being
the most frequently occurring type. After a stroke, neutrophils accumulate in the brain and …

Prolonged myelin deficits contribute to neuron loss and functional impairments after ischaemic stroke

YJ Cheng, F Wang, J Feng, B Yu, B Wang, Q Gao… - Brain, 2024 - academic.oup.com
Ischaemic stroke causes neuron loss and long-term functional deficits. Unfortunately,
effective approaches to preserving neurons and promoting functional recovery remain …

Optimal systolic and diastolic blood pressure threshold that associated with lower risk of white matter hyperintensity progression

S Liu, M Wang, D Gu, Y Li, X Zhang, H Li… - Frontiers in Aging …, 2023 - frontiersin.org
Background The optimal control thresholds for systolic blood pressure (SBP) and diastolic
blood pressure (DBP) in patients with white matter hyperintensity (WMH) are still unclear …

[HTML][HTML] Argon neuroprotection in ischemic stroke and its underlying mechanism

L Bao, Y Liu, Q Jia, S Chu, H Jiang - Brain Research Bulletin, 2024 - Elsevier
Ischemic stroke (IS), primarily caused by cerebrovascular obstruction, results in severe
neurological deficits and has emerged as a leading cause of death and disability worldwide …

Development and validation of a fusion model based on carotid plaques and white matter lesion burden imaging characteristics to evaluate ischemic stroke severity in …

Z Cui, S Xu, J Miu, Y Tang, L Pan… - Journal of Magnetic …, 2025 - Wiley Online Library
Background The diagnostic value of carotid plaque characteristics based on higher–
resolution vessel wall MRI (HRVW‐MRI) combined with white matter lesion (WML) burden …

Greater burden of white matter lesions and silent infarcts ipsilateral to carotid stenosis

MP Lin, M Demirer, EH Middlebrooks, RG Tawk… - Journal of Stroke and …, 2023 - Elsevier
Objectives Carotid stenosis may cause silent cerebrovascular disease (CVD) through
atheroembolism and hypoperfusion. If so, revascularization may slow progression of silent …

The predictors of death within 1 year in acute ischemic stroke patients based on machine learning

K Wang, L Gu, W Liu, C Xu, C Yin, H Liu… - Frontiers in …, 2023 - frontiersin.org
Objective To explore the predictors of death in acute ischemic stroke (AIS) patients within 1
year based on machine learning (ML) algorithms. Methods This study retrospectively …

Structural Disconnections Caused by White Matter Hyperintensities in Post‐Stroke Spatial Neglect

L Röhrig, HO Karnath - Human Brain Map**, 2024 - Wiley Online Library
White matter hyperintensities (WMH), a common feature of cerebral small vessel disease,
affect a wide range of cognitive dysfunctions, including spatial neglect. The latter is a …

Is Broca's area critical for speech and language? Evidence from lesion-symptom map** in chronic aphasia

TJ Herron, K Schendel, BC Curran, SJ Lwi… - Frontiers in Language …, 2024 - frontiersin.org
Introduction The specific role that Broca's area plays in speech and language has been hotly
debated in the literature. Some research has pointed to a specific role in particular aspects …

Analysis of risk factors for white matter hyperintensity in older adults without stroke

K Zheng, Z Wang, X Chen, J Chen, Y Fu, Q Chen - Brain Sciences, 2023 - mdpi.com
Background: White matter hyperintensity (WMH) is prevalent in older adults aged 60 and
above. A large proportion of people with WMH have not experienced stroke and little has …