A review of MRI findings in schizophrenia
After more than 100 years of research, the neuropathology of schizophrenia remains
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …
unknown and this is despite the fact that both: Kraepelin, E., 1919/1971. Dementia praecox …
“Cognitive dysmetria” as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry?
Earlier efforts to localize the symptoms of schizophrenia in a single brain region have been
replaced by models that postulate a disruption in parallel distributed or dynamic circuits …
replaced by models that postulate a disruption in parallel distributed or dynamic circuits …
Meta-analysis of regional brain volumes in schizophrenia
OBJECTIVE: The authors' goal was to determine whether patients with schizophrenia differ
from comparison subjects in regional brain volumes and whether these differences are …
from comparison subjects in regional brain volumes and whether these differences are …
Hippocampal volume reduction in schizophrenia as assessed by magnetic resonance imaging: a meta-analytic study
MD Nelson, AJ Saykin, LA Flashman… - Archives of general …, 1998 - jamanetwork.com
Background Although many quantitative magnetic resonance imaging studies have found
significant volume reductions in the hippocampi of patients with schizophrenia compared …
significant volume reductions in the hippocampi of patients with schizophrenia compared …
Brain abnormality in schizophrenia: a systematic and quantitative review of volumetric magnetic resonance imaging studies
SM Lawrie, SS Abukmeil - The British Journal of Psychiatry, 1998 - cambridge.org
BackgroundNumerous in vivo brain imaging studies suggest that cerebral Structure is
abnormal in schizophrenia, but implicate different regions to varying extents. MethodWe …
abnormal in schizophrenia, but implicate different regions to varying extents. MethodWe …
MRI anatomy of schizophrenia
Structural magnetic resonance imaging (MRI) data have provided much evidence in support
of our current view that schizophrenia is a brain disorder with altered brain structure, and …
of our current view that schizophrenia is a brain disorder with altered brain structure, and …
Abnormally high neuronal density in the schizophrenic cortex: a morphometric analysis of prefrontal area 9 and occipital area 17
LD Selemon, G Rajkowska… - Archives of general …, 1995 - jamanetwork.com
Background: In the past two decades, gross morphologic changes have been uncovered in
the schizophrenic brain, eg, increased ventricular width and decreased cortical volume; …
the schizophrenic brain, eg, increased ventricular width and decreased cortical volume; …
MR-based in vivo hippocampal volumetrics: 2. Findings in neuropsychiatric disorders
Magnetic resonance imaging (MRI) has opened a new window to the brain. Measuring
hippocampal volume with MRI has provided important information about several …
hippocampal volume with MRI has provided important information about several …
Schizophrenia as an anomaly of development of cerebral asymmetry: a postmortem study and a proposal concerning the genetic basis of the disease
TJ Crow, J Ball, SR Bloom, R Brown… - Archives of general …, 1989 - jamanetwork.com
• Schizophrenia is associated with structural changes (eg, a mild degree of ventricular
enlargement) in the brain, although whether these precede onset of illness or progress with …
enlargement) in the brain, although whether these precede onset of illness or progress with …
Molecular aspects of glutamate dysregulation: implications for schizophrenia and its treatment
The glutamate system is involved in many aspects of neuronal synaptic strength and
function during development and throughout life. Synapse formation in early brain …
function during development and throughout life. Synapse formation in early brain …