The role of fibroblast growth factor 18 in cancers: functions and signaling pathways

Y Zhou, S Sun, T Ling, Y Chen, R Zhou, Q You - Frontiers in Oncology, 2023 - frontiersin.org
Fibroblast growth factor 18 (FGF18) is a member of the fibroblast growth factor family (FGFs).
FGF18 is a class of bioactive substances that can conduct biological signals, regulate cell …

Bioinformatics screening of colorectal-cancer causing molecular signatures through gene expression profiles to discover therapeutic targets and candidate agents

MA Horaira, MA Islam, MK Kibria, MJ Alam… - BMC Medical …, 2023 - Springer
Background Detection of appropriate receptor proteins and drug agents are equally
important in the case of drug discovery and development for any disease. In this study, an …

Integrated analysis of necroptosis-related genes for prognosis, immune microenvironment infiltration, and drug sensitivity in colon cancer

R He, M Zhang, L He, J Huang, C Man, X Wang… - Frontiers in …, 2022 - frontiersin.org
Background Necroptosis, is intimately linked to tumor development and prognosis and has
been considered as a target for anticancer therapy. However, the role of necroptosis-related …

Elucidating the anti-aging mechanism of Si Jun Zi Tang by integrating network pharmacology and experimental validation in vivo

Y Yuan, Y Zhang, R Zheng, H Yuan, R Zhou… - Aging (Albany …, 2022 - pmc.ncbi.nlm.nih.gov
Si Jun Zi Tang (SJZT) is a classic Traditional Chinese Medicine (TCM) prescription used to
treat aging-related diseases. However, the potential molecular mechanisms of the anti-aging …

Prognosis prediction of stage IV colorectal cancer patients by mRNA transcriptional profile

B Wu, J Yang, Z Qin, H Yang, J Shao… - Cancer …, 2022 - Wiley Online Library
Background Stage IV colorectal cancer patients with liver metastasis represent a special
group of CRC patients with poor prognosis. The prognostic factors have not been …

Construction and verification of a novel prognostic risk model for kidney renal clear cell carcinoma based on immunity-related genes

Y Liu, D Wu, H Chen, L Yan, Q **ang, Q Li… - Frontiers in …, 2023 - frontiersin.org
Background: Currently, there are no useful biomarkers or prognostic risk markers for the
diagnosis of kidney renal clear cell carcinoma (KIRC), although recent research has shown …

Osteosarcoma-associated immune genes as potential immunotherapy and prognosis biomarkers

L Yang, Y Long, S **ao - Biochemical Genetics, 2024 - Springer
Immune-modulating therapies exhibit abundant promise compared to traditional treatment
for osteosarcoma. We aim to establish an immune-related prognostic signatures in …

Comprehensive analysis of cellular senescence and immune microenvironment in papillary thyroid carcinoma

Y Huang, H Jiang, G Xu, X Li, W Chen… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
Senescence-induced therapy was previously considered as an effective treatment for
tumors, and cellular senescence was initially regarded as an effective mechanism against …

Prognostic analysis and risk assessment based on RNA editing in hepatocellular carcinoma

X Shi, X Bu, X Zhou, N Shen, Y Chang, W Yu… - Journal of Applied …, 2024 - Springer
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, and
prognosis assessment is crucial for guiding treatment decisions. In this study, we aimed to …

Anti-ccr8 antibodies for treating cancer

RYZ Lan, OA Adelakun, I Barman… - US Patent App. 17 …, 2023 - Google Patents
2021-06-23 Assigned to BRISTOL-MYERS SQUIBB COMPANY reassignment BRISTOL-
MYERS SQUIBB COMPANY ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …