In vivo identification of astrocyte and neuron subproteomes by proximity-dependent biotinylation

JS Soto, Y Jami-Alahmadi, JA Wohlschlegel… - Nature …, 2024 - nature.com
The central nervous system (CNS) comprises diverse and morphologically complex cells. To
understand the molecular basis of their physiology, it is crucial to assess proteins expressed …

Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14

M Wang, Z Zhong, J Gallego-Bartolomé, S Feng… - Nature …, 2023 - nature.com
Arabidopsis telomeric repeat binding factors (TRBs) can bind telomeric DNA sequences to
protect telomeres from degradation. TRBs can also recruit Polycomb Repressive Complex 2 …

Histone chaperone ASF1 mediates H3. 3-H4 deposition in Arabidopsis

Z Zhong, Y Wang, M Wang, F Yang, QA Thomas… - Nature …, 2022 - nature.com
Histone chaperones and chromatin remodelers control nucleosome dynamics, which are
essential for transcription, replication, and DNA repair. The histone chaperone Anti …

Elucidation of TRIM25 ubiquitination targets involved in diverse cellular and antiviral processes

E Yang, S Huang, Y Jami-Alahmadi… - PLoS …, 2022 - journals.plos.org
The tripartite motif (TRIM) family of E3 ubiquitin ligases is well known for its roles in antiviral
restriction and innate immunity regulation, in addition to many other cellular pathways. In …

The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated+ 1 nucleosome positioning and transcription start site determination in Arabidopsis

B Diego-Martin, J Pérez-Alemany… - Nucleic Acids …, 2022 - academic.oup.com
Eukaryotes have evolved multiple ATP-dependent chromatin remodelers to shape the
nucleosome landscape. We recently uncovered an evolutionarily conserved SWItch/Sucrose …

Comprehensive identification of SWI/SNF complex subunits underpins deep eukaryotic ancestry and reveals new plant components

J Hernández-García, B Diego-Martin, PH Kuo… - Communications …, 2022 - nature.com
Over millions of years, eukaryotes evolved from unicellular to multicellular organisms with
increasingly complex genomes and sophisticated gene expression networks. Consequently …

Map** of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome

P Sanfilippo, AJ Kim, A Bhukel, J Yoo, PS Mirshahidi… - Neuron, 2024 - cell.com
Neurons express various combinations of neurotransmitter receptor (NR) subunits and
receive inputs from multiple neuron types expressing different neurotransmitters. Localizing …

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

M Oravcová, M Nie, N Zilio, S Maeda, Y Jami-Alahmadi… - Elife, 2022 - elifesciences.org
The human SMC5/6 complex is a conserved guardian of genome stability and an emerging
component of antiviral responses. These disparate functions likely require distinct …

Direct tests of cytochrome c and c1 functions in the electron transport chain of malaria parasites

TJ Espino-Sanchez, H Wienkers… - Proceedings of the …, 2023 - National Acad Sciences
The mitochondrial electron transport chain (ETC) of Plasmodium malaria parasites is a
major antimalarial drug target, but critical cytochrome (cyt) functions remain unstudied and …

SP3‐FAIMS‐enabled high‐throughput quantitative profiling of the cysteinome

HS Desai, T Yan, KM Backus - Current Protocols, 2022 - Wiley Online Library
Cysteine‐directed chemoproteomic profiling methods yield high‐throughput inventories of
redox‐sensitive and ligandable cysteine residues and therefore are enabling techniques for …