The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

Aliphatic azides are a versatile class of compounds found in a variety of biologically active
pharmaceuticals. These compounds are also recognized as useful precursors for the …

The 1, 2-diamine motif is prevalent in natural products, small-molecule pharmaceuticals, and
catalysts for asymmetric synthesis. Transition metal catalyzed alkene diazidation has …

The asymmetric catalytic synthesis of 1, 2-diamines has received considerable interest,
especially in the last ten years, due to their presence in biologically active compounds and …

Due to the overuse of antibiotics, bacterial resistance has markedly increased to become a
global problem and a major threat to human health. Fortunately, in recent years, various new …

All pharmaceutical products contain organic molecules; the source may be a natural product
or a fully synthetic molecule, or a combination of both. Thus, it follows that organic chemistry …

Transition-metal-catalyzed remote hydrofunctionalization of alkenes remains an efficient but
challenging protocol in chemical synthesis. Herein, we reported a ligand-controlled …

Piperazine and homopiperazine are well-studied heterocycles in drug design that have
found gainful application as scaffolds and terminal elements and for enhancing the aqueous …

The ability to efficiently synthesize desired compounds can be a limiting factor for chemical
space exploration in drug discovery. This ability is conditioned not only by the existence of …

An efficient kinetic resolution of racemic trans-2, 3-aziridinyl alcohols is established via zinc
catalyzed ring opening reactions with various amines as the nucleophiles. The directing …