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Insulin resistance in children
VM Tagi, C Giannini, F Chiarelli - Frontiers in endocrinology, 2019 - frontiersin.org
Insulin resistance (IR) is a pathological condition strongly associated with obesity. However,
corticosteroids or growth hormone therapy and genetic diseases may affect insulin …
corticosteroids or growth hormone therapy and genetic diseases may affect insulin …
Insulin-resistance in paediatric age: Its magnitude and implications
Insulin resistance (IR) is insulin failure in normal plasma levels to adequately stimulate
glucose uptake by the peripheral tissues. IR is becoming more common in children and …
glucose uptake by the peripheral tissues. IR is becoming more common in children and …
Recent developments in antimalarial drug discovery
T Umumararungu, JB Nkuranga, G Habarurema… - Bioorganic & Medicinal …, 2023 - Elsevier
Although malaria remains a big burden to many countries that it threatens their socio-
economic stability, particularly in the countries where malaria is endemic, there have been …
economic stability, particularly in the countries where malaria is endemic, there have been …
In Vitro and in silico studies to explore potent antidiabetic inhibitor against human pancreatic alpha-amylase from the methanolic extract of the green microalga …
Today's era and lifestyle have led to a quick rise in cases of diabetes. Diabetes mellitus (DM)
has risen to the top of the list of serious diseases and stems from different health disorders …
has risen to the top of the list of serious diseases and stems from different health disorders …
Phytochemical Profiling in Conjunction with In Vitro and In Silico Studies to Identify Human α-Amylase Inhibitors in Leucaena leucocephala (Lam.) De Wit for the …
Bioactive constituents from natural sources are of great interest as alternatives to synthetic
compounds for the treatment of various diseases, including diabetes mellitus. In the present …
compounds for the treatment of various diseases, including diabetes mellitus. In the present …
c4c: Paediatric pharmacovigilance: Methodological considerations in research and development of medicines for children–A c4c expert group white paper
B Aurich, D Apele‐Freimane… - British journal of …, 2022 - Wiley Online Library
Children frequently respond differently to therapies compared to adults. Differences also
exist between paediatric age groups for pharmacokinetics and pharmacodynamics in both …
exist between paediatric age groups for pharmacokinetics and pharmacodynamics in both …
Utility of quantitative proteomics for enhancing the predictive ability of physiologically based pharmacokinetic models across disease states
S Sharma, D Suresh Ahire… - The Journal of Clinical …, 2020 - Wiley Online Library
Disease states such as liver cirrhosis and chronic kidney disease can lead to altered
pharmacokinetics (PK) of drugs by influencing drug absorption, blood flow to organs, plasma …
pharmacokinetics (PK) of drugs by influencing drug absorption, blood flow to organs, plasma …
Effects of metformin on epicardial adipose tissue and atrial electromechanical delay of obese children with insulin resistance
Introduction: Obesity is usually related to insulin resistance and glucose metabolism
disorders. The relationship between insulin resistance and epicardial adipose tissue and …
disorders. The relationship between insulin resistance and epicardial adipose tissue and …
[HTML][HTML] The Clinical Pharmacokinetics and Pharmacodynamics of Glimepiride—A Systematic Review and Meta-Analysis
Background/Objectives: Glimepiride (GLM), a commonly used sulphonylurea drug for the
management of type 2 diabetes mellitus (T2DM), has been the subject of numerous studies …
management of type 2 diabetes mellitus (T2DM), has been the subject of numerous studies …
Improvement of high-glucose and insulin resistance of chromium malate in 3T3-L1 adipocytes by glucose uptake and insulin sensitivity signaling pathways and its …
W Feng, Y Liu, F Fei, Y Chen, Y Ding, M Yan, Y Feng… - RSC …, 2019 - pubs.rsc.org
Previous study has revealed that chromium malate could improve insulin resistance and the
regulation of fasting blood glucose in type 2 diabetic rats. This study was designed to …
regulation of fasting blood glucose in type 2 diabetic rats. This study was designed to …