Aquaporins: water channel proteins of the cell membrane

K Takata, T Matsuzaki, Y Tajika - Progress in histochemistry and …, 2004 - Elsevier
Aquaporins (AQP) are integral membrane proteins that serve as channels in the transfer of
water, and in some cases, small solutes across the membrane. They are conserved in …

Expression, distribution and role of aquaporin water channels in human and animal stomach and intestines

C Zhu, Z Chen, Z Jiang - International journal of molecular sciences, 2016 - mdpi.com
Stomach and intestines are involved in the secretion of gastrointestinal fluids and the
absorption of nutrients and fluids, which ensure normal gut functions. Aquaporin water …

Aquaporin water channels in gastrointestinal physiology

T Ma, AS Verkman - The Journal of physiology, 1999 - Wiley Online Library
Fluid transport is a major function of the gastrointestinal (GI) tract with more than 9 litres of
fluid being absorbed or secreted across epithelia in human salivary gland, stomach, the …

Water channel proteins in the gastrointestinal tract

U Laforenza - Molecular aspects of medicine, 2012 - Elsevier
Water transport through the human digestive system is physiologically crucial for
maintaining body water homeostasis and ensure digestive and absorptive functions. Within …

Aquaporin water channels and lung physiology

AS Verkman, MA Matthay… - American Journal of …, 2000 - journals.physiology.org
Fluid transport across epithelial and endothelial barriers occurs in the neonatal and adult
lungs. Biophysical measurements in the intact lung and cell isolates have indicated that …

pH and calcium regulate the water permeability of aquaporin 0

KL Németh-Cahalan, JE Hall - Journal of Biological Chemistry, 2000 - jbc.org
Aquaporins increase the water permeability in many cell types across many species. We
investigated the effects of external pH and Ca 2+ on water permeability ofXenopus oocytes …

Impaired hearing in mice lacking aquaporin-4 water channels

J Li, AS Verkman - Journal of Biological Chemistry, 2001 - jbc.org
A role for aquaporins (AQPs) in hearing has been suggested from the specific expression of
aquaporins in inner ear and the need for precise volume regulation in epithelial cells …

The human AQP4 gene: definition of the locus encoding two water channel polypeptides in brain.

M Lu, MD Lee, BL Smith, JS Jung, P Agre… - Proceedings of the …, 1996 - pnas.org
The aquaporin family of membrane water transport proteins are expressed in diverse
tissues, and in brain the predominant water channel protein is AQP4. Here we report the …

Neuromyelitis optica pathogenesis and aquaporin 4

DJ Graber, M Levy, D Kerr, WF Wade - Journal of neuroinflammation, 2008 - Springer
Neuromyelitis optica (NMO) is a severe, debilitating human disease that predominantly
features immunopathology in the optic nerves and the spinal cord. An IgG1 autoantibody …

Expression and localization of aquaporins in rat gastrointestinal tract

Y Koyama, T Yamamoto, T Tani… - … of Physiology-Cell …, 1999 - journals.physiology.org
A family of water-selective channels, aquaporins (AQP), has been demonstrated in various
organs and tissues. However, the localization and expression of the AQP family members in …