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Epigenetic regulation in metabolic diseases: mechanisms and advances in clinical study
YL Wu, ZJ Lin, CC Li, X Lin, SK Shan, B Guo… - … and Targeted Therapy, 2023 - nature.com
Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …
Role of oxidative stress in the pathogenesis of non-alcoholic fatty liver disease: implications for prevention and therapy
JC Arroyave-Ospina, Z Wu, Y Geng, H Moshage - Antioxidants, 2021 - mdpi.com
Oxidative stress (OxS) is considered a major factor in the pathophysiology of inflammatory
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
chronic liver diseases, including non-alcoholic liver disease (NAFLD). Chronic impairment of …
Hesperetin ameliorates hepatic oxidative stress and inflammation via the PI3K/AKT-Nrf2-ARE pathway in oleic acid-induced HepG2 cells and a rat model of high-fat …
J Li, T Wang, P Liu, F Yang, X Wang, W Zheng… - Food & function, 2021 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is considered the most common liver disease.
Dietary supplementation has become a promising strategy for managing NAFLD …
Dietary supplementation has become a promising strategy for managing NAFLD …
Bioactive compounds in oxidative stress-mediated diseases: targeting the NRF2/ARE signaling pathway and epigenetic regulation
M Thiruvengadam, B Venkidasamy, U Subramanian… - Antioxidants, 2021 - mdpi.com
Oxidative stress is a pathological condition occurring due to an imbalance between the
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …
oxidants and antioxidant defense systems in the body. Nuclear factor E2-related factor 2 …
New insights and potential therapeutic interventions in metabolic diseases
Endocrine homeostasis and metabolic diseases have been the subject of extensive
research in recent years. The development of new techniques and insights has led to a …
research in recent years. The development of new techniques and insights has led to a …
Treatment for liver cancer: From sorafenib to natural products
S Man, C Luo, M Yan, G Zhao, L Ma, W Gao - European journal of …, 2021 - Elsevier
Liver cancer most commonly develops in patients with chronic liver disease, the etiology of
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
Signaling pathways related to oxidative stress in diabetic cardiomyopathy
M Peng, Y Fu, C Wu, Y Zhang, H Ren… - Frontiers in …, 2022 - frontiersin.org
Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …
Epigenetics in NAFLD/NASH: Targets and therapy
Recently non-alcoholic fatty liver disease (NAFLD) has grabbed considerable scientific
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …
attention, owing to its rapid increase in prevalence worldwide and growing burden on end …
Efficacy and safety of dietary polyphenol supplementation in the treatment of non-alcoholic fatty liver disease: A systematic review and meta-analysis
Background Dietary polyphenol treatment of non-alcoholic fatty liver disease (NAFLD) is a
novel direction, and the existing clinical studies have little effective evidence for its …
novel direction, and the existing clinical studies have little effective evidence for its …
Progress in the treatment of drug-induced liver injury with natural products
Y Sun, Y Zhang, L **e, F Rong, X Zhu, J **e… - Pharmacological …, 2022 - Elsevier
There are numerous prescription drugs and non-prescription drugs that cause drug-induced
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …
liver injury (DILI), which is the main cause of liver disease in humans around the globe. Its …