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Asymptomatic malaria infections: detectability, transmissibility and public health relevance
Most Plasmodium falciparum infections that are detected in community surveys are
characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular …
characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular …
malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Epidemiology and infectivity of Plasmodium falciparum and Plasmodium vivax gametocytes in relation to malaria control and elimination
Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …
falciparum responsible for the majority of the disease burden and P. vivax being the …
Submicroscopic Infection in Plasmodium falciparum-Endemic Populations: A Systematic Review and Meta-Analysis
Introduction Light microscopy examination of blood slides is the main method of detecting
malaria infection; however, it has limited sensitivity. Low-density infections are most likely to …
malaria infection; however, it has limited sensitivity. Low-density infections are most likely to …
Dynamics of the human infectious reservoir for malaria determined by mosquito feeding assays and ultrasensitive malaria diagnosis in Burkina Faso
A Lin Ouédraogo, BP Gonçalves… - The Journal of …, 2016 - academic.oup.com
Background Plasmodium falciparum gametocytes are essential for malaria transmission.
Malaria control measures that aim at reducing transmission require an accurate …
Malaria control measures that aim at reducing transmission require an accurate …
Substantial Contribution of Submicroscopical Plasmodium falciparum Gametocyte Carriage to the Infectious Reservoir in an Area of Seasonal Transmission
Background Man to mosquito transmission of malaria depends on the presence of the
sexual stage parasites, gametocytes, that often circulate at low densities. Gametocyte …
sexual stage parasites, gametocytes, that often circulate at low densities. Gametocyte …
Targeting human transmission biology for malaria elimination
Malaria remains one of the leading causes of death worldwide, despite decades of public
health efforts. The recent commitment by many endemic countries to eliminate malaria …
health efforts. The recent commitment by many endemic countries to eliminate malaria …
Blood-Stage Parasitaemia and Age Determine Plasmodium falciparum and P. vivax Gametocytaemia in Papua New Guinea
A better understanding of human-to-mosquito transmission is crucial to control malaria. In
order to assess factors associated with gametocyte carriage, 2083 samples were collected …
order to assess factors associated with gametocyte carriage, 2083 samples were collected …
Assessing the infectious reservoir of falciparum malaria: past and future
Renewed interest in malaria eradication has placed greater emphasis on the development
of tools to interrupt Plasmodium transmission, such as transmission-blocking vaccines …
of tools to interrupt Plasmodium transmission, such as transmission-blocking vaccines …
Predominance of asymptomatic and sub-microscopic infections characterizes the Plasmodium gametocyte reservoir in the Peruvian Amazon
E Rovira-Vallbona, JJ Contreras-Mancilla… - PLoS neglected …, 2017 - journals.plos.org
Malaria transmission requires that Anopheles mosquitoes ingest Plasmodium gametocyte
stages circulating in the human bloodstream. In the context of malaria elimination …
stages circulating in the human bloodstream. In the context of malaria elimination …