The basement membrane is an important extracellular matrix that is found in all epithelial
and endothelial tissues. It maintains tissue integrity, serves as a barrier to cells and to …

Approximately one-third of patients with stroke exhibit persistent disability after the initial
cerebrovascular episode, with motor impairments accounting for most poststroke disability …

Cell therapies for neurological disorders are entering the clinic and present unique
challenges and opportunities compared with conventional medicines. They have the …

Hypoxic-ischemic brain injury is a significant cause of morbidity and mortality in the adult as
well as in the neonate. Extensive pre-clinical studies have shown promising therapeutic …

In recent years, stem cell‐based approaches have attracted more attention from scientists
and clinicians due to their possible therapeutical effect on stroke. Animal studies have …

Stroke usually causes prolonged or lifelong disability, owing to the permanent loss of
infarcted tissue. Although a variety of stem cell transplantation has been explored to improve …

The regeneration of tissues and organs poses an immense challenge due to the extreme
complexity in the research work involved. Despite the tissue engineering approach being …

Diseases and injuries of the central nervous system (CNS) including those in the brain,
spinal cord and retina are devastating because the CNS has limited intrinsic regenerative …

Stem cell-based therapies are steadily gaining traction for regenerative medicine
approaches to treating disease and injury throughout the body. While a significant body of …

Human neural stem/progenitor cells (hNSPCs) are good candidates for treating central
nervous system (CNS) trauma since they secrete beneficial trophic factors and differentiate …