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Accurately identifying hemagglutinin using sequence information and machine learning methods
Introduction Hemagglutinin (HA) is responsible for facilitating viral entry and infection by
promoting the fusion between the host membrane and the virus. Given its significance in the …
promoting the fusion between the host membrane and the virus. Given its significance in the …
H2Opred: a robust and efficient hybrid deep learning model for predicting 2'-O-methylation sites in human RNA
O-methylation (2OM) is the most common post-transcriptional modification of RNA. It plays a
crucial role in RNA splicing, RNA stability and innate immunity. Despite advances in high …
crucial role in RNA splicing, RNA stability and innate immunity. Despite advances in high …
Bitter-RF: a random forest machine model for recognizing bitter peptides
YF Zhang, YH Wang, ZF Gu, XR Pan, J Li… - Frontiers in …, 2023 - frontiersin.org
Introduction Bitter peptides are short peptides with potential medical applications. The huge
potential behind its bitter taste remains to be tapped. To better explore the value of bitter …
potential behind its bitter taste remains to be tapped. To better explore the value of bitter …
iRNA-ac4C: a novel computational method for effectively detecting N4-acetylcytidine sites in human mRNA
W Su, XQ **e, XW Liu, D Gao, CY Ma, H Zulfiqar… - International Journal of …, 2023 - Elsevier
Abstract RNA N4-acetylcytidine (ac4C) is the acetylation of cytidine at the nitrogen-4
position, which is a highly conserved RNA modification and involves a variety of biological …
position, which is a highly conserved RNA modification and involves a variety of biological …
A computational model of circRNA-associated diseases based on a graph neural network: prediction and case studies for follow-up experimental validation
Abstract Background Circular RNAs (circRNAs) have been confirmed to play a vital role in
the occurrence and development of diseases. Exploring the relationship between circRNAs …
the occurrence and development of diseases. Exploring the relationship between circRNAs …
i2OM: Toward a better prediction of 2′-O-methylation in human RNA
YH Yang, CY Ma, D Gao, XW Liu, SS Yuan… - International Journal of …, 2023 - Elsevier
O-methylation (2OM) is an omnipresent post-transcriptional modification in RNAs. It is
important for the regulation of RNA stability, mRNA splicing and translation, as well as innate …
important for the regulation of RNA stability, mRNA splicing and translation, as well as innate …
Computational approaches for predicting drug-disease associations: a comprehensive review
Z Huang, Z **ao, C Ao, L Guan, L Yu - Frontiers of Computer Science, 2025 - Springer
In recent decades, traditional drug research and development have been facing challenges
such as high cost, long timelines, and high risks. To address these issues, many …
such as high cost, long timelines, and high risks. To address these issues, many …
Deep-AGP: Prediction of angiogenic protein by integrating two-dimensional convolutional neural network with discrete cosine transform
Angiogenic proteins (AGPs) play a primary role in the formation of new blood vessels from
pre-existing ones. AGPs have diverse applications in cancer, including serving as …
pre-existing ones. AGPs have diverse applications in cancer, including serving as …
ncRS: A resource of non-coding RNAs in sepsis
B Zhong, Y Dai, L Chen, X Xu, Y Lan, L Deng… - Computers in Biology …, 2024 - Elsevier
Sepsis, a life-threatening condition triggered by the body's response to infection, presents a
significant global healthcare challenge characterized by disarrayed host responses …
significant global healthcare challenge characterized by disarrayed host responses …
[HTML][HTML] GPApred: The first computational predictor for identifying proteins with LPXTG-like motif using sequence-based optimal features
The cell surface proteins of gram-positive bacteria are involved in many important biological
functions, including the infection of host cells. Owing to their virulent nature, these proteins …
functions, including the infection of host cells. Owing to their virulent nature, these proteins …