[HTML][HTML] Moringa oleifera leaf extract induces osteogenic-like differentiation of human osteosarcoma SaOS2 cells
Introduction Moringa oleifera is known as a 'natural nutrition of the tropics' because it
provides vital nutritional supplements and a variety of pharmacological benefits. The focus of …
provides vital nutritional supplements and a variety of pharmacological benefits. The focus of …
Structural and Functional Annotation of Hypothetical Proteins from the Microsporidia Species Vittaforma corneae ATCC 50505 Using in silico Approaches
Microsporidia are spore-forming eukaryotes that are related to fungi but have unique traits
that set them apart. They have compact genomes as a result of evolutionary gene loss …
that set them apart. They have compact genomes as a result of evolutionary gene loss …
Binding site characterization–similarity, promiscuity, and druggability
C Ehrt, T Brinkjost, O Koch - Medchemcomm, 2019 - pubs.rsc.org
The elucidation of non-obvious binding site similarities has provided useful indications for
the establishment of polypharmacology, the identification of potential off-targets, or the …
the establishment of polypharmacology, the identification of potential off-targets, or the …
Exploring the binding affinity and non-covalent interactions of anthocyanins with aging-related enzymes through molecular docking
JSB Nas - Philippine Journal of Health Research and …, 2020 - pjhrd.upm.edu.ph
Abstract Background and Objective: Anthocyanins are associated with aging and longevity.
However, the mechanism involving the pure anthocyanin compounds in aging remains …
However, the mechanism involving the pure anthocyanin compounds in aging remains …
Specifics of metabolite-protein interactions and their computational analysis and prediction
D Walther - Cell-Wide Identification of Metabolite-Protein …, 2022 - Springer
Computational approaches to the characterization and prediction of compound-protein
interactions have a long research history and are well established, driven primarily by the …
interactions have a long research history and are well established, driven primarily by the …
Comparative assessment of the therapeutic drug targets of C. botulinum ATCC 3502 and C. difficile str. 630 using in silico subtractive proteomics approach
Growing antimicrobial resistance of the pathogens against multiple drugs posed a serious
threat to the human health worldwide. This fueled the need of identifying the novel …
threat to the human health worldwide. This fueled the need of identifying the novel …
Identification of phytocompounds as potent inhibitors of sodium/glucose cotransporter-2 leading to diabetes treatment
A Swargiary, M Daimari, A Swargiary… - Journal of …, 2024 - Taylor & Francis
Type-II diabetes, a major metabolic disorder has threatened the very existence of a healthy
life since long ago. Commercially available antidiabetic drugs are known for several adverse …
life since long ago. Commercially available antidiabetic drugs are known for several adverse …
Roles of Physicochemical and Structural Properties of RNA-Binding Proteins in Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning
L Zhu, W Li - International Journal of Molecular Sciences, 2022 - mdpi.com
Trans-acting splicing factors play a pivotal role in modulating alternative splicing by
specifically binding to cis-elements in pre-mRNAs. There are approximately 1500 RNA …
specifically binding to cis-elements in pre-mRNAs. There are approximately 1500 RNA …
Spatial proximity statistics suggest a regulatory role of protein phosphorylation on compound binding
Phosphorylation is an important post‐translational modification that regulates protein
function by the attachment of negatively charged phosphate groups to phosphorylatable …
function by the attachment of negatively charged phosphate groups to phosphorylatable …
Anthocyanin-Binding Affinity and Non-Covalent Interactions with IIS-Pathway-Related Protein Through Molecular Docking
Z Khan, W Javaid, LX **ng - Current Issues in Molecular Biology, 2025 - mdpi.com
Anthocyanins compounds, including cyanidin, malvidin, pelargonidin, peonidin, and
petunidin, have demonstrated remarkable anti-aging and insulin-sensitizing properties …
petunidin, have demonstrated remarkable anti-aging and insulin-sensitizing properties …