In the physiological condition, the skeletal system's bone resorption and formation are in
dynamic balance, called bone homeostasis. However, bone homeostasis is destroyed under …

Deferoxamine (DFO) has been in use for half a century as a Food and Drug Administration-
approved iron chelator, but recent studies indicate a variety of properties that could expand …

Abstract 3D printed scaffolds hold promising perspective for bone tissue regeneration.
Inspired by process of bone development stage, 3D printed scaffolds with rapid internal …

In clinical treatment, the bone regeneration of critical‐size defects is desiderated to be
solved, and the regeneration of large bone segment defects depends on early …

Osteoporosis is one of the most disabling consequences of aging, osteoporotic fractures and
higher risk of the subsequent fractures leading to substantial disability and deaths, indicating …

Controlled delivery systems play a critical role in the success of bone morphogenetic
proteins (ie, BMP2 and BMP7) for challenged bone repair. Instead of single-drug release …

Microorganisms induced wound infection and the accompanying excessive inflammatory
response is the daunting problems in wound treatment. Due to the lack of corresponding …

The escalating prevalence of anterior cruciate ligament (ACL) injuries in sports necessitates
innovative strategies for ACL reconstruction. In this study, we propose a multiphasic bone …

It has been a major challenge to treat osteoporotic bone defects with irregular shapes.
Although bioactive glass offers an attractive material for bone regeneration, its inherent …

Background Cell behavior is the key to tissue regeneration. Given the fact that most of the
cells used in tissue engineering are anchorage-dependent, their behavior including …