Versatile delivery systems for non-platinum metal-based anticancer therapeutic agents
Y Gou, GJ Huang, J Li, F Yang, H Liang - Coordination chemistry reviews, 2021 - Elsevier
Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …
severe side effects. Therefore, extensive research has been performed to design and …
Metallocompounds as anticancer agents against osteosarcoma
Metallocompounds are a class of anticancer compounds largely used in the treatment of
several types of solid tumors, including bone cancer. Osteosarcoma (OS) is a primary …
several types of solid tumors, including bone cancer. Osteosarcoma (OS) is a primary …
Promising Dual Anticancer and Antimetastatic Action by a Cu (II) Complex Derived from Acylhydrazone on Human Osteosarcoma Models
Osteosarcoma cancers are becoming more common in children and young adults, and
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
existing treatments have low efficacy and a very high mortality rate, making it pressing to …
Regulated Cu Diatomic Distance Promoting Carbon−Carbon Coupling During CO2 Electroreduction
To address the bottle‐neck carbon‐carbon coupling issue during electrochemical carbon
dioxide reduction (eCO2RR) to multicarbon (C2+) products, this work develops an anion …
dioxide reduction (eCO2RR) to multicarbon (C2+) products, this work develops an anion …
Cu (II)-acylhydrazone complex, a potent and selective antitumor agent against human osteosarcoma: Mechanism of action studies over in vitro and in vivo models
Osteosarcoma (OS) is a frequent bone cancer, affecting largely children and young adults.
Cisplatin (CDDP) has been efficacious in the treatment of different cancer such us OS but …
Cisplatin (CDDP) has been efficacious in the treatment of different cancer such us OS but …
Deciphering the Effect of a Cu (II)‐hydrazone Complex on Intracellular Cell Signalling Pathways in a Human Osteosarcoma 2D and 3D Models
New therapeutic strategies for osteosarcoma (OS) have demonstrated the potential efficacy
of copper compounds as anticancer drugs and as a substitute for the often used platinum …
of copper compounds as anticancer drugs and as a substitute for the often used platinum …
Effect of Metal Environment and Immobilization on the Catalytic Activity of a Cu Superoxide Dismutase Mimic
The Cu (II)/Cu (I) conversion involves variation in the coordination number and geometry
around the metal center. Therefore, the flexibility/rigidity of the ligand plays a critical role in …
around the metal center. Therefore, the flexibility/rigidity of the ligand plays a critical role in …
[HTML][HTML] Roles and mechanisms of copper homeostasis and cuproptosis in osteoarticular diseases
J Han, J Luo, C Wang, L Kapilevich, X Zhang - Biomedicine & …, 2024 - Elsevier
Copper is an essential trace element in the human body that is extensively distributed
throughout various tissues. The appropriate level of copper is crucial to maintaining the life …
throughout various tissues. The appropriate level of copper is crucial to maintaining the life …
Copper (II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1, 10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper (II) …
NJS Bontempo, DA Paixão, PMAP Lima, DCT Barros… - Molecules, 2022 - mdpi.com
Prostate Cancer (PCa) is the second leading cause of cancer-related deaths among men
worldwide. The treatment of advanced cases is based on chemotherapy, which lacks …
worldwide. The treatment of advanced cases is based on chemotherapy, which lacks …
DNA/bovine serum albumin binding and cytotoxicity of transition metal ternary complexes based on sulfamethazine and bromazepam drugs
Similar to the antibiotic mixing strategies, which depend on reducing the worth of diffusion of
the resistant bacteria to new host, in this contribution, we explicit new mixed‐ligand …
the resistant bacteria to new host, in this contribution, we explicit new mixed‐ligand …