[HTML][HTML] HIV-1 drug resistance mutations: an updated framework for the second decade of HAART
RW Shafer, JM Schapiro - AIDS reviews, 2008 - ncbi.nlm.nih.gov
More than 200 mutations are associated with antiretroviral resistance to drugs belonging to
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …
six licensed antiretroviral classes. More than 50 reverse transcriptase mutations are …
HIV entry inhibitors
JA Esté, A Telenti - The Lancet, 2007 - thelancet.com
The need for new classes of antiretroviral drugs has become apparent because of
increasing concern about the long-term toxic effects of existing drugs, the need to combat …
increasing concern about the long-term toxic effects of existing drugs, the need to combat …
HIV-1 induced bystander apoptosis
Apoptosis of uninfected bystander cells is a key element of HIV pathogenesis and believed
to be the driving force behind the selective depletion of CD4+ T cells leading to …
to be the driving force behind the selective depletion of CD4+ T cells leading to …
Algae-mediated processes for the treatment of antiretroviral drugs in wastewater: prospects and challenges
The prevalence of pharmaceuticals (PCs), especially antiretroviral (ARV) drugs in various
aquatic ecosystems has been expansively reported, wherein wastewater treatment plants …
aquatic ecosystems has been expansively reported, wherein wastewater treatment plants …
The Effect of treatment-associated mutations on HIV replication and transmission cycles
MM Johnson, CE Jones, DN Clark - Viruses, 2022 - mdpi.com
HIV/AIDS mortality has been decreasing over the last decade. While promising, this
decrease correlated directly with increased use of antiretroviral drugs. As a natural …
decrease correlated directly with increased use of antiretroviral drugs. As a natural …
HIV diagnosis and treatment through advanced technologies
Human immunodeficiency virus (HIV) is the chief contributor to global burden of disease. In
2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages …
2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages …
Mechanisms underlying of antiretroviral drugs in different cellular reservoirs with a focus on macrophages
S Aquaro, A Borrajo, M Pellegrino, V Svicher - Virulence, 2020 - Taylor & Francis
Ongoing with current combinations of antiretroviral drugs for the treatment of Human
Immunodeficiency Virus (HIV) infection can successfully maintain long-term suppression of …
Immunodeficiency Virus (HIV) infection can successfully maintain long-term suppression of …
Resistance of human immunodeficiency virus type 1 to a third-generation fusion inhibitor requires multiple mutations in gp41 and is accompanied by a dramatic loss of …
D Eggink, I Bontjer, JPM Langedijk, B Berkhout… - Journal of …, 2011 - Am Soc Microbiol
ABSTRACT HIV-1 entry into target cells requires the fusion of viral and cellular membranes.
This process is an attractive target for therapeutic intervention, and a first-generation fusion …
This process is an attractive target for therapeutic intervention, and a first-generation fusion …
Host and viral factors in HIV-mediated bystander apoptosis
Human immunodeficiency virus (HIV) infections lead to a progressive loss of CD4 T cells
primarily via the process of apoptosis. With a limited number of infected cells and vastly …
primarily via the process of apoptosis. With a limited number of infected cells and vastly …
Genome-Wide Association Study Implicates PARD3B-Based AIDS Restriction
JL Troyer, GW Nelson, JA Lautenberger… - Journal of Infectious …, 2011 - academic.oup.com
Background. Host genetic variation influences human immunodeficiency virus (HIV)
infection and progression to AIDS. Here we used clinically well-characterized subjects from …
infection and progression to AIDS. Here we used clinically well-characterized subjects from …