The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Cancer vaccines are the promising tools in the hands of the clinical oncologist. Many tumor-
associated antigens are excellent targets for immune therapy and vaccine design. Optimally …

A major impediment to the successful application of gene therapy for the treatment of a
range of diseases is not a paucity of therapeutic genes, but the lack of an efficient non‐toxic …

CFTR Modulators for the Treatment of Cystic Fibrosis - PMC Back to Top Skip to main content
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This review describes the challenges and therapeutic applications of nanodelivery systems
for treatment of airway diseases. Therapeutic applications of nanodelivery in airway …

Targeted gene therapy is essential if cancer treatment is to become a reality with this form of
therapy. In the past few years, cationic liposomes, discovered 2 decades ago, and at …

Cystic fibrosis (CF) is the most frequent lethal genetic disease in the Caucasian population.
Lung destruction is the principal cause of death by chronic Pseudomonas aeruginosa …

Genetic modification therapy is a promising therapeutic strategy for many diseases of the
lung intractable to other treatments. Lung gene therapy has been the subject of numerous …

Cystic fibrosis (CF) is a life-limiting disease caused by defective or deficient cystic fibrosis
transmembrane conductance regulator (CFTR) activity. The recent advent of the FDA …

Advances in DNA-and RNA-based technologies have made gene therapy suitable for many
lung diseases, especially those that are hereditary. The main objective of gene therapy is to …