Non-mutational neoantigens in disease
The ability of mammals to mount adaptive immune responses culminating with the
establishment of immunological memory is predicated on the ability of the mature T cell …
establishment of immunological memory is predicated on the ability of the mature T cell …
Immunopeptidomics for autoimmunity: unlocking the chamber of immune secrets
T cells mediate pathogenesis of several autoimmune disorders by recognizing self-epitopes
presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) …
presented on Major Histocompatibility Complex (MHC) or Human Leukocyte Antigen (HLA) …
The cryptic immunopeptidome in health and disease
Peptides presented by MHC proteins regulate all aspects of T cell biology. These MHC-
associated peptides (MAPs) form what is known as the immunopeptidome and their …
associated peptides (MAPs) form what is known as the immunopeptidome and their …
Pan-viral ORFs discovery using Massively Parallel Ribosome Profiling
Unveiling the complete proteome of viruses is crucial to our understanding of the viral life
cycle and interaction with the host. We developed Massively Parallel Ribosome Profiling …
cycle and interaction with the host. We developed Massively Parallel Ribosome Profiling …
Comparative analysis of protein expression between oesophageal adenocarcinoma and normal adjacent tissue
Oesophageal adenocarcinoma (OAC) is the 7th most common cancer in the United
Kingdom and remains a significant health challenge. This study presents a proteomic …
Kingdom and remains a significant health challenge. This study presents a proteomic …