Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a natural
product class that has undergone significant expansion due to the rapid growth in genome …

Covering: up to June 2020 Ribosomally-synthesized and post-translationally modified
peptides (RiPPs) are a large group of natural products. A community-driven review in 2013 …

Genetically encoded small molecules (secondary metabolites) play eminent roles in
ecological interactions, as pathogenicity factors and as drug leads. Yet, these chemical …

Novel antibiotics are urgently needed to address the looming global crisis of antibiotic
resistance. Historically, the primary source of clinically used antibiotics has been microbial …

The field of mycology has grown from an underappreciated subset of botany, to a valuable,
modern scientific discipline. As this field of study has grown, there have been significant …

Bacteria provide a rich source of natural products with potential therapeutic applications,
such as novel antibiotic classes or anticancer drugs. Bioactivity-guided screening of …

Ribosomally synthesized and post-translationally modified peptide (RiPP) natural products
are attractive for genome-driven discovery and re-engineering, but limitations in …

Lanthipeptides are ribosomally synthesized and post-translationally modified peptides
(RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic …

Microbial natural products represent a rich resource of pharmaceutically and industrially
important compounds. Genome sequencing has revealed that the majority of natural …

Covering: 2010 to 2021 Organisms in nature have evolved into proficient synthetic chemists,
utilizing specialized enzymatic machinery to biosynthesize an inspiring diversity of …