Disease-modifying drugs have mostly failed as treatments for progressive multiple sclerosis.
Management of the disease therefore solely aims to minimise symptoms and, if possible …

Pain is common in patients with multiple sclerosis (MS), but estimates of its prevalence have
varied widely. The literature describing pain in MS patients spans four decades and has …

Abstract Background The Patient Determined Disease Steps (PDDS) is a promising patient-
reported outcome (PRO) of disability in multiple sclerosis (MS). To date, there is limited …

Fatigue is one of the most common debilitating symptoms reported by persons with multiple
sclerosis (MS). It reflects feelings of tiredness, lack of energy, low motivation, and difficulty in …

Physical activity has been associated with a small improvement in quality of life (QOL)
among those with multiple sclerosis (MS). This relationship may be indirect and operate …

Abstract Purpose of Review Pharmaceutical cannabinoids such as nabiximols, nabilone and
dronabinol, and plant-based cannabinoids have been investigated for their therapeutic …

Jensen MP, Moore MR, Bockow TB, Ehde DM, Engel JM. Psychosocial factors and
adjustment to chronic pain in persons with physical disabilities: a systematic review …

Multiple sclerosis (MS) is associated with significant economic burden and high rates of
unemployment. This investigation evaluated patient and disease characteristics associated …

Objectives To investigate levels of moderate-to-vigorous physical activity (MVPA) in a large
sample of persons with multiple sclerosis (MS) and controls using accelerometry as a …

Pain is a common symptom in multiple sclerosis (MS) and has recently been estimated to be
experienced by up to 75% of patients. Pain can be present at any point in the course of the …