Single-molecule localization microscopy

M Lelek, MT Gyparaki, G Beliu, F Schueder… - Nature reviews …, 2021 - nature.com
Single-molecule localization microscopy (SMLM) describes a family of powerful imaging
techniques that dramatically improve spatial resolution over standard, diffraction-limited …

Adaptive optics for high-resolution imaging

KM Hampson, R Turcotte, DT Miller… - Nature Reviews …, 2021 - nature.com
Adaptive optics (AO) is a technique that corrects for optical aberrations. It was originally
proposed to correct for the blurring effect of atmospheric turbulence on images in ground …

Super-resolution microscopy demystified

L Schermelleh, A Ferrand, T Huser, C Eggeling… - Nature cell …, 2019 - nature.com
Super-resolution microscopy (SRM) bypasses the diffraction limit, a physical barrier that
restricts the optical resolution to roughly 250 nm and was previously thought to be …

Super-resolution microscopy for structural cell biology

S Liu, P Hoess, J Ries - Annual review of biophysics, 2022 - annualreviews.org
Super-resolution microscopy techniques, and specifically single-molecule localization
microscopy (SMLM), are approaching nanometer resolution inside cells and thus have great …

Visualizing and discovering cellular structures with super-resolution microscopy

YM Sigal, R Zhou, X Zhuang - Science, 2018 - science.org
Super-resolution microscopy has overcome a long-held resolution barrier—the diffraction
limit—in light microscopy and enabled visualization of previously invisible molecular details …

Fluorescence nanoscopy in cell biology

SJ Sahl, SW Hell, S Jakobs - Nature reviews Molecular cell biology, 2017 - nature.com
Fluorescence nanoscopy uniquely combines minimally invasive optical access to the
internal nanoscale structure and dynamics of cells and tissues with molecular detection …

Isotropic super-resolution light-sheet microscopy of dynamic intracellular structures at subsecond timescales

Y Zhao, M Zhang, W Zhang, Y Zhou, L Chen, Q Liu… - Nature …, 2022 - nature.com
Long-term visualization of the dynamic interactions between intracellular structures
throughout the three-dimensional space of whole live cells is essential to better understand …

Adaptive optical fluorescence microscopy

N Ji - Nature methods, 2017 - nature.com
The past quarter century has witnessed rapid developments of fluorescence microscopy
techniques that enable structural and functional imaging of biological specimens at …

Three-dimensional localization of single molecules for super-resolution imaging and single-particle tracking

L von Diezmann, Y Shechtman, WE Moerner - Chemical reviews, 2017 - ACS Publications
Single-molecule super-resolution fluorescence microscopy and single-particle tracking are
two imaging modalities that illuminate the properties of cells and materials on spatial scales …

PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection

D Xu, W Jiang, L Wu, RG Gaudet, ES Park, M Su… - Nature, 2023 - nature.com
Understanding protective immunity to COVID-19 facilitates preparedness for future
pandemics and combats new SARS-CoV-2 variants emerging in the human population …