Plasmodium vivax in the era of the shrinking P. falciparum map
Plasmodium vivax is an important cause of malaria, associated with a significant public
health burden. Whilst enhanced malaria-control activities have successfully reduced the …
health burden. Whilst enhanced malaria-control activities have successfully reduced the …
Effect of primaquine dose on the risk of recurrence in patients with uncomplicated Plasmodium vivax: a systematic review and individual patient data meta-analysis
Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …
dosing regimen remains unclear. We undertook a systematic review and individual patient …
Lineage-informative microhaplotypes for recurrence classification and spatio-temporal surveillance of Plasmodium vivax malaria parasites
Challenges in classifying recurrent Plasmodium vivax infections constrain surveillance of
antimalarial efficacy and transmission. Recurrent infections may arise from activation of …
antimalarial efficacy and transmission. Recurrent infections may arise from activation of …
Can the future of ID escape the inertial dogma of its past? The exemplars of shorter is better and oral is the new IV
K Davar, D Clark, RM Centor… - Open Forum …, 2023 - academic.oup.com
Like all fields of medicine, Infectious Diseases is rife with dogma that underpins much
clinical practice. In this study, we discuss 2 specific examples of historical practice that have …
clinical practice. In this study, we discuss 2 specific examples of historical practice that have …
Primaquine dose and the risk of haemolysis in patients with uncomplicated Plasmodium vivax malaria: a systematic review and individual patient data meta-analysis
Background Primaquine radical cure is used to treat dormant liver-stage parasites and
prevent relapsing Plasmodium vivax malaria but is limited by concerns of haemolysis. We …
prevent relapsing Plasmodium vivax malaria but is limited by concerns of haemolysis. We …
[HTML][HTML] Estimating the proportion of Plasmodium vivax recurrences caused by relapse: a systematic review and meta-analysis
Plasmodium vivax and Plasmodium ovale form dormant liver hypnozoites that can reactivate
weeks to months following initial infection. Malaria recurrences caused by relapses are an …
weeks to months following initial infection. Malaria recurrences caused by relapses are an …
The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis
Tafenoquine is a newly licensed antimalarial drug for the radical cure of Plasmodium vivax
malaria. The mechanism of action and optimal dosing are uncertain. We pooled individual …
malaria. The mechanism of action and optimal dosing are uncertain. We pooled individual …
[HTML][HTML] Plasmodium vivax–How hidden reservoirs hinder global malaria elimination
Plasmodium vivax is the most geographically widespread human malaria parasite. Global
malaria efforts have been less successful at reducing the burden of P. vivax compared to P …
malaria efforts have been less successful at reducing the burden of P. vivax compared to P …
8-Aminoquinoline therapy for latent malaria
JK Baird - Clinical Microbiology Reviews, 2019 - Am Soc Microbiol
The technical genesis and practice of 8-aminoquinoline therapy of latent malaria offer
singular scientific, clinical, and public health insights. The 8-aminoquinolines brought …
singular scientific, clinical, and public health insights. The 8-aminoquinolines brought …
Advances and roadblocks in the treatment of malaria
B Hanboonkunupakarn, NJ White - British journal of clinical …, 2022 - Wiley Online Library
The deployment of artesunate for severe malaria and the artemisinin combination therapies
(ACTs) for uncomplicated malaria has been a major advance in antimalarial therapeutics …
(ACTs) for uncomplicated malaria has been a major advance in antimalarial therapeutics …