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Disappearing polymorphs revisited
DK Bučar, RW Lancaster… - Angewandte Chemie …, 2015 - Wiley Online Library
Nearly twenty years ago, Dunitz and Bernstein described a selection of intriguing cases of
polymorphs that disappear. The inability to obtain a crystal form that has previously been …
polymorphs that disappear. The inability to obtain a crystal form that has previously been …
Supercritical fluids in chemistry
Dedicated the memory of Akademician Valery Vasilievich Lunin, a friend, colleague,
teacher, founder and leader of the research into application of supercritical fluids in …
teacher, founder and leader of the research into application of supercritical fluids in …
[HTML][HTML] A practical guide to pharmaceutical polymorph screening & selection
EH Lee - Asian Journal of Pharmaceutical Sciences, 2014 - Elsevier
Prevalence and importance of polymorphism occurring in pharmaceutical compounds are
well recognized. It is of great importance to prepare and select the right form from the …
well recognized. It is of great importance to prepare and select the right form from the …
Solid form screening–a review
Solid form screening, the activity of generating and analysing different solid forms of an
active pharmaceutical ingredient (API), has become an essential part of drug development …
active pharmaceutical ingredient (API), has become an essential part of drug development …
Role of additives in crystal nucleation from solutions: a review
S Xu, D Cao, Y Liu, Y Wang - Crystal Growth & Design, 2021 - ACS Publications
Nucleation is a key step in the crystallization of solution. For regulating and controlling this
process, it is thus critical to understand the nucleation mechanism under different …
process, it is thus critical to understand the nucleation mechanism under different …
Why don't we find more polymorphs?
SL Price - Structural Science, 2013 - journals.iucr.org
Crystal structure prediction (CSP) studies are not limited to being a search for the most
thermodynamically stable crystal structure, but play a valuable role in understanding …
thermodynamically stable crystal structure, but play a valuable role in understanding …
Simultaneously improving the mechanical properties, dissolution performance, and hygroscopicity of ibuprofen and flurbiprofen by cocrystallization with nicotinamide
Purpose To be fully exploitable in both formulation and manufacturing, a drug cocrystal
needs to demonstrate simultaneous improvement of multiple key pharmaceutical properties …
needs to demonstrate simultaneous improvement of multiple key pharmaceutical properties …
Polymorphism and crystallization of active pharmaceutical ingredients (APIs)
Active pharmaceutical ingredients (APIs), frequently delivered to the patient in the solid-state
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
as part of an approved dosage form, can exist in such diverse solid forms as polymorphs …
Polymorphism and solvatomorphism 2010
HG Brittain - Journal of pharmaceutical sciences, 2012 - Elsevier
Papers and patents that deal with polymorphism (crystal systems for which a substance can
exist in structures defined by different unit cells and where each of the forms has the same …
exist in structures defined by different unit cells and where each of the forms has the same …
From crystal structure prediction to polymorph prediction: interpreting the crystal energy landscape
SL Price - Physical Chemistry Chemical Physics, 2008 - pubs.rsc.org
Many organic molecules are emerging as having many crystalline forms, including
polymorphs and solvates, as more techniques are being used to generate and characterise …
polymorphs and solvates, as more techniques are being used to generate and characterise …