Tumor necrosis factor (TNF)-α is a pleiotropic cytokine that exerts host-damaging effects in
different autoimmune and inflammatory diseases. It is a key regulator of other …

A considerable body of experimental evidence suggests that tumor necrosis factor (TNF)‐α
plays a major role in several aspects of inflammation and shock. In particular, it is pivotal in …

Background: It is now generally accepted that chronic pancreatic injury and fibrosis may
result from repeated episodes of acute pancreatic necroinflammation (the necrosis-fibrosis …

Activation of the inhibitor of NF-κB kinase/NF-κB (IKK/NF-κB) system and expression of
proinflammatory mediators are major events in acute pancreatitis. However, the in vivo …

p8 is a transcription cofactor whose expression is strongly and rapidly activated in
pancreatic acinar cells during the acute phase of pancreatitis. A p8-deficient mouse strain …

The aim of the present review is to summarize the current knowledge regarding
pharmacological prevention and treatment of acute pancreatitis (AP) based on experimental …

Recent studies using experimental models of acute pancreatitis suggest that events blocking
evoked secretion of digestive enzymes from acinar cells may play an important role in the …

Inflammation is one of the most natural ways of the body's biological response against
invading foreign pathogens or injured cells which eventually can lead to a chronic or acute …

Abstract Background and Aim Acute pancreatitis (AP) is a rare extraintestinal manifestation
of inflammatory bowel disease (IBD). Several studies from Western countries have reported …

Methods The case reports of 1,500 liver transplant patients were reviewed. Orthotopic liver
transplantation (OLT) patients were matched 1: 2 with non-OLT patients and followed-up for …