Exosomal circRNAs: biogenesis, effect and application in human diseases
Exosomes have emerged as critical mediators of intercellular communication, both locally
and systemically, by regulating a diverse range of biological processes between cells …
and systemically, by regulating a diverse range of biological processes between cells …
Cancer stem cells as key drivers of tumour progression
Abstract Background Cancer stem cells (CSCs) are subpopulations of cancer cells sharing
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …
similar characteristics as normal stem or progenitor cells such as self-renewal ability and …
The origin and pathogenesis of endometriosis
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …
modified model in which circulating epithelial progenitor or stem cells intended to …
Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future
SR Li, QW Man, X Gao, H Lin, J Wang… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are lipid‐bilayer membrane structures secreted by most cell
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …
types. EVs act as messengers via the horizontal transfer of lipids, proteins, and nucleic …
Cancer-associated fibroblast exosomes regulate survival and proliferation of pancreatic cancer cells
KE Richards, AE Zeleniak, ML Fishel, J Wu… - Oncogene, 2017 - nature.com
Cancer-associated fibroblasts (CAFs) comprise the majority of the tumor bulk of pancreatic
ductal adenocarcinomas (PDACs). Current efforts to eradicate these tumors focus …
ductal adenocarcinomas (PDACs). Current efforts to eradicate these tumors focus …
Mesenchymal stem cell-derived exosomes as a new therapeutic strategy for liver diseases
The administration of mesenchymal stem cells (MSCs) as a therapy for liver disease holds
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
great promise. MSCs can differentiate into hepatocytes, reduce liver inflammation, promote …
Extracellular vesicles: new classification and tumor immunosuppression
Simple Summary Extracellular vesicles (EVs) are cell-derived membrane-surrounded
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
vesicles that carry bioactive molecules and deliver them to recipient cells. Classical EVs are …
The extracellular matrix alteration, implication in modulation of drug resistance mechanism: friends or foes?
A Jurj, C Ionescu, I Berindan-Neagoe… - Journal of Experimental & …, 2022 - Springer
The extracellular matrix (ECM) is an important component of the tumor microenvironment
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …
(TME), having several important roles related to the hallmarks of cancer. In cancer, multiple …
CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA
Background CD90+ liver cancer cells have been described as cancer stem-cell-like (CSC),
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …
displaying aggressive and metastatic phenotype. Using two different in vitro models, already …
Cardiac progenitor cell-derived exosomes prevent cardiomyocytes apoptosis through exosomal miR-21 by targeting PDCD4
J **ao, Y Pan, XH Li, XY Yang, YL Feng, HH Tan… - Cell death & …, 2016 - nature.com
Cardiac progenitor cells derived from adult heart have emerged as one of the most
promising stem cell types for cardiac protection and repair. Exosomes are known to mediate …
promising stem cell types for cardiac protection and repair. Exosomes are known to mediate …