2024 ESC Guidelines for the management of elevated blood pressure and hypertension: Developed by the task force on the management of elevated blood pressure …
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …
off-label use of medication should be limited to situations where it is in the patient's interest …
The sirtuin family in health and disease
QJ Wu, TN Zhang, HH Chen, XF Yu, JL Lv… - … and Targeted Therapy, 2022 - nature.com
Sirtuins (SIRTs) are nicotine adenine dinucleotide (+)-dependent histone deacetylases
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
regulating critical signaling pathways in prokaryotes and eukaryotes, and are involved in …
2023 AHA/ACC/ACCP/ASPC/NLA/PCNA guideline for the management of patients with chronic coronary disease: a report of the American Heart Association …
Writing Committee Members, SS Virani… - Journal of the American …, 2023 - jacc.org
Abstract Aim The “2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …
of Patients With Chronic Coronary Disease” provides an update to and consolidates new …
[HTML][HTML] Empagliflozin in patients with chronic kidney disease
EMPA-Kidney Collaborative Group - New England Journal of …, 2023 - Mass Medical Soc
Background The effects of empagliflozin in patients with chronic kidney disease who are at
risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed …
risk for disease progression are not well understood. The EMPA-KIDNEY trial was designed …
Cardiovascular-kidney-metabolic health: a presidential advisory from the American Heart Association
Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors,
chronic kidney disease, and the cardiovascular system and has profound impacts on …
chronic kidney disease, and the cardiovascular system and has profound impacts on …
Trends in insulin resistance: insights into mechanisms and therapeutic strategy
M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …
Chronic kidney disease
Chronic kidney disease is a progressive disease with no cure and high morbidity and
mortality that occurs commonly in the general adult population, especially in people with …
mortality that occurs commonly in the general adult population, especially in people with …
Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options
J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …
[HTML][HTML] Global pandemics interconnected—obesity, impaired metabolic health and COVID-19
Obesity and impaired metabolic health are established risk factors for the non-
communicable diseases (NCDs) type 2 diabetes mellitus, cardiovascular disease …
communicable diseases (NCDs) type 2 diabetes mellitus, cardiovascular disease …
The fibrogenic niche in kidney fibrosis: components and mechanisms
L Li, H Fu, Y Liu - Nature Reviews Nephrology, 2022 - nature.com
Kidney fibrosis, characterized by excessive deposition of extracellular matrix (ECM) that
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …
leads to tissue scarring, is the final common outcome of a wide variety of chronic kidney …