Fluorine-18 radiochemistry, labeling strategies and synthetic routes
Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET)
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
radiopharmaceuticals in both clinical and preclinical research. Its physical and nuclear …
Peptide-based agents for cancer treatment: current applications and future directions
Peptide-based strategies have received an enormous amount of attention because of their
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
specificity and applicability. Their specificity and tumor-targeting ability are applied to …
[HTML][HTML] Clinical application of radiolabeled RGD peptides for PET imaging of integrin αvβ3
Molecular imaging for non-invasive assessment of angiogenesisis is of great interest for
clinicians because of the wide-spread application of anti-angiogenic cancer therapeutics …
clinicians because of the wide-spread application of anti-angiogenic cancer therapeutics …
[HTML][HTML] Imaging of macrophage mitochondria dynamics in vivo reveals cellular activation phenotype for diagnosis
Highly plastic macrophages are pivotal players in the body's homeostasis and
pathogenesis. Gras** the molecular or cellular factors that drive and support the …
pathogenesis. Gras** the molecular or cellular factors that drive and support the …
A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate Labeling?
Due to its ideal physical properties, fluorine-18 turns out to be a key radionuclide for positron
emission tomography (PET) imaging, for both preclinical and clinical applications. However …
emission tomography (PET) imaging, for both preclinical and clinical applications. However …
Radionuclide imaging and therapy directed towards the tumor microenvironment: A multi-cancer approach for personalized medicine
CD van der Heide, SU Dalm - European Journal of Nuclear Medicine and …, 2022 - Springer
Targeted radionuclide theranostics is becoming more and more prominent in clinical
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …
oncology. Currently, most nuclear medicine compounds researched for cancer theranostics …
Molecular imaging of myocardial inflammation with positron emission tomography post-ischemia: a determinant of subsequent remodeling or recovery
JT Thackeray, FM Bengel - JACC: Cardiovascular Imaging, 2018 - jacc.org
Inflammation after myocardial ischemia influences ventricular remodeling and repair and
has emerged as a therapeutic target. Conventional diagnostic measurements address …
has emerged as a therapeutic target. Conventional diagnostic measurements address …
[HTML][HTML] Positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging of macrophages in large vessel vasculitis: current …
Macrophages are key players in the pathogenesis of large-vessel vasculitis (LVV) and may
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …
serve as a target for diagnostic imaging of LVV. The radiotracer, 18 F-FDG has proven to be …
In vivo albumin labeling and lymphatic imaging
Y Wang, L Lang, P Huang, Z Wang… - Proceedings of the …, 2015 - National Acad Sciences
The ability to accurately and easily locate sentinel lymph nodes (LNs) with noninvasive
imaging methods would assist in tumor staging and patient management. For this purpose …
imaging methods would assist in tumor staging and patient management. For this purpose …
Radiolabelled peptides for positron emission tomography and endoradiotherapy in oncology
C Rangger, R Haubner - Pharmaceuticals, 2020 - mdpi.com
This review deals with the development of peptide-based radiopharmaceuticals for the use
with positron emission tomography and peptide receptor radiotherapy. It discusses the pros …
with positron emission tomography and peptide receptor radiotherapy. It discusses the pros …