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[HTML][HTML] An overview on target-based drug design against kinetoplastid protozoan infections: Human African trypanosomiasis, Chagas disease and leishmaniases
The protozoan diseases Human African Trypanosomiasis (HAT), Chagas disease (CD), and
leishmaniases span worldwide and therefore their impact is a universal concern. The …
leishmaniases span worldwide and therefore their impact is a universal concern. The …
[HTML][HTML] The translational challenge in Chagas disease drug development
Chagas disease is a neglected tropical disease caused by the protozoan parasite
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …
Trypanosoma cruzi. There is an urgent need for safe, effective, and accessible new …
Current leishmaniasis drug discovery
AC Pinheiro, MVN de Souza - RSC Medicinal Chemistry, 2022 - pubs.rsc.org
Leishmaniasis is a complex protozoan infectious disease and, associated with malnutrition,
poor health services and unavailability of prophylactic control measures, neglected …
poor health services and unavailability of prophylactic control measures, neglected …
[HTML][HTML] Recent progress in the development of indole-based compounds active against malaria, trypanosomiasis and leishmaniasis
PAF Pacheco, MMM Santos - Molecules, 2022 - mdpi.com
Human protozoan diseases represent a serious health problem worldwide, affecting mainly
people in social and economic vulnerability. These diseases have attracted little investment …
people in social and economic vulnerability. These diseases have attracted little investment …
Liposomal drug delivery systems for the treatment of leishmaniasis
Human le ishmaniasis is a vector-borne, neglected infectious disease that is widely
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …
distributed in America, Africa, Europe, and Asia. Current therapy is based on old and toxic …
[HTML][HTML] Effects of propolis on infectious diseases of medical relevance
N Rivera-Yanez, CR Rivera-Yanez, G Pozo-Molina… - Biology, 2021 - mdpi.com
Simple Summary Propolis is a beekee** product with a complex and highly variable
chemical composition. Many beneficial health properties have been reported. In this review …
chemical composition. Many beneficial health properties have been reported. In this review …
Bioprospecting marine actinomycetes for antileishmanial drugs: current perspectives and future prospects
Revived analysis interests in natural products in the hope of discovering new and novel
antileishmanial drug leads have been driven partially by the increasing incidence of drug …
antileishmanial drug leads have been driven partially by the increasing incidence of drug …
Leishmania Animal Models Used in Drug Discovery: A Systematic Review
J van der Ende, HDFH Schallig - Animals, 2023 - mdpi.com
Simple Summary Animals are frequently used to determine whether new compounds have
the potential to be used as drugs against the parasitic disease leishmaniasis. There is …
the potential to be used as drugs against the parasitic disease leishmaniasis. There is …
Experimental structure based drug design (SBDD) applications for anti‐leishmanial drugs: A paradigm shift?
M Marín, M López, L Gallego‐Yerga… - Medicinal Research …, 2024 - Wiley Online Library
Leishmaniasis is a group of neglected tropical diseases caused by at least 20 species of
Leishmania protozoa, which are spread by the bite of infected sandflies. There are three …
Leishmania protozoa, which are spread by the bite of infected sandflies. There are three …
Approved drugs successfully repurposed against Leishmania based on machine learning predictions
R Oualha, YZ Abdelkrim, I Guizani… - Frontiers in Cellular …, 2024 - frontiersin.org
Drug repurposing is a promising approach towards the discovery of novel treatments against
Neglected Tropical Diseases, such as Leishmaniases, presenting the advantage of reducing …
Neglected Tropical Diseases, such as Leishmaniases, presenting the advantage of reducing …