Two-component systems reprogramme diverse aspects of microbial physiology in response
to environmental cues. Canonical systems are composed of a transmembrane sensor …

Perceiving environmental and internal information and reacting in adaptive ways are
essential attributes of living organisms. Two-component systems are relevant protein …

Response regulators function as the output components of two-component systems, which
couple the sensing of environmental stimuli to adaptive responses. Response regulators …

The evolution of novel functions in biology relies heavily on gene duplication and
divergence, creating large paralogous protein families. Selective pressure to avoid …

Bacteria must constantly probe their environment for rapid adaptation, a crucial need most
frequently served by two-component systems (TCS). As one component, sensor histidine …

The rise of public and other non-recreational digital services is based on the idea of catering
to the daily needs of the citizens cost-efficiently and with ease. Previous research has …

Numerous photoreceptors and genetic circuits emerged over the past two decades and now
enable the light-dependent ie, optogenetic, regulation of gene expression in bacteria …

Bacterial phytochrome photoreceptors usually belong to two-component signaling systems
which transmit environmental stimuli to a response regulator through a histidine kinase …

Bacterial two-component systems (TCSs) are signaling modules that control physiology,
adaptation, and host interactions. A typical TCS consists of a histidine kinase (HK) that …

Two‐component systems (TCS) constitute the predominant means by which prokaryotes
read out and adapt to their environment. Canonical TCSs comprise a sensor histidine kinase …