Nitric oxide (NO) is a highly reactive molecule, generated through metabolism of L-arginine
by NO synthase (NOS). Abnormal NO levels in mammalian cells are associated with multiple …

Coconut, Cocos nucifera L., is a tree that is cultivated to provide a large number of products,
although it is mainly grown for its nutritional and medicinal values. Coconut oil, derived from …

As a functional amino acid (AA), L-arginine (Arg) serves not only as a building block of
protein but also as an essential substrate for the synthesis of nitric oxide (NO), creatine …

Type 2 diabetes has become a global public health problem affecting approximately 380
million people throughout the world. It can cause many complications and lead to greater …

Reactive oxygen species (ROS) have been mainly viewed as unwanted by-products of
cellular metabolism, oxidative stress, a sign of a cellular redox imbalance, and potential …

Metabolic adaptation to a disturbance of homeostasis is determined by a series of
interconnected physiological processes and molecular mechanisms that can be followed in …

Nitric oxide (NO) is a ubiquitous, endogenously produced, water-soluble signaling molecule
playing critical roles in physiological processes. Nitric oxide plays pleiotropic roles in cancer …

Hypertension remains an important modifiable risk factor for cardiovascular disease,
associated with increased morbidity and mortality. Deciphering the mechanisms involved in …

S-nitrosylation is a selective and reversible post-translational modification of protein thiols by
nitric oxide (NO), which is a bioactive signaling molecule, to exert a variety of effects. These …

Background and aims Gestational diabetes mellitus (GDM) is a pathological condition of
glucose intolerance associated with adverse pregnancy outcomes and increased risk of …