[HTML][HTML] Advances in aptameric biosensors designed to detect toxic contaminants from food, water, human fluids, and the environment

US Kadam, JC Hong - Trends in Environmental Analytical Chemistry, 2022 - Elsevier
Detection of toxic small molecule contaminants with sensitivity, accuracy, and specificity is a
challenging task. Traditionally used HPLC and mass spectrometry-based assays suffer from …

Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets

US Kadam, Y Cho, TY Park, JC Hong - Applied biological chemistry, 2023 - Springer
CRISPR-Cas systems have been widely used in genome editing and transcriptional
regulation. Recently, CRISPR-Cas effectors are adopted for biosensor construction due to its …

Advancements in CRISPR-based biosensing for next-gen point of care diagnostic application

A Kumaran, N Jude Serpes, T Gupta, A James… - Biosensors, 2023 - mdpi.com
With the move of molecular tests from diagnostic labs to on-site testing becoming more
common, there is a sudden rise in demand for nucleic acid-based diagnostic tools that are …

[HTML][HTML] Unraveling the mechanisms of virus-induced symptom development in plants

T Jiang, T Zhou - Plants, 2023 - mdpi.com
Plant viruses, as obligate intracellular parasites, induce significant changes in the cellular
physiology of host cells to facilitate their multiplication. These alterations often lead to the …

Assessment of genetic diversity and volatile content of commercially grown banana (Musa spp.) cultivars

VR Hinge, IM Shaikh, RL Chavhan, AS Deshmukh… - Scientific Reports, 2022 - nature.com
Banana is an important fruit crop in the tropics and subtropics; however, limited information
on biomarkers and signature volatiles is available for selecting commercial cultivars. Clonal …

[HTML][HTML] CRISPR/Cas12a-based biosensors for environmental monitoring and diagnostics

AK Wani, N Akhtar, C Chopra, R Singh, JC Hong… - … Technology & Innovation, 2024 - Elsevier
Contaminants, such as nucleic acids or toxic small molecules, threaten both human health
and ecosystems when they infiltrate the environment. The precise and highly sensitive …

Barley stripe mosaic virus-mediated somatic and heritable gene editing in barley (Hordeum vulgare L.)

S Tamilselvan-Nattar-Amutha, S Hiekel… - Frontiers in Plant …, 2023 - frontiersin.org
Genome editing strategies in barley (Hordeum vulgare L.) typically rely on Agrobacterium-
mediated genetic transformation for the delivery of required genetic reagents involving …

Strategies and methods for improving the efficiency of CRISPR/Cas9 gene editing in plant molecular breeding

J Zhou, X Luan, Y Liu, L Wang, J Wang, S Yang, S Liu… - Plants, 2023 - mdpi.com
Following recent developments and refinement, CRISPR-Cas9 gene-editing technology has
become increasingly mature and is being widely used for crop improvement. The application …

Plant protection against viruses: an integrated review of plant immunity agents

M Huang, Z Wu, J Li, Y Ding, S Chen, X Li - International Journal of …, 2023 - mdpi.com
Plant viruses are an important class of pathogens that seriously affect plant growth and harm
crop production. Viruses are simple in structure but complex in mutation and have thus …

Advancements in bionanotechnological applications for climate-smart agriculture and food production

S Otari, VA Bapat, J Lakkakula, US Kadam… - Biocatalysis and …, 2024 - Elsevier
Due to the significant challenges of growing global population and climate change, the
agriculture and food industries are facing a continued demand for improving productivity …