Considered by some to be among the simpler forms of life, viruses represent highly evolved
natural vectors for the transfer of foreign genetic information into cells. This attribute has led …

Publisher Summary This chapter discusses the common properties of tailed phages and
potential criteria for their classification as an order and situating tailed phages with respect to …

This report updates, expands, and replaces the previously published CDC" Guideline for
Prevention of Nosocomial Pneumonia". The new guidelines are designed to reduce the …

Recombinant adenoviruses provide a versatile system for gene expression studies and
therapeutic applications. We have developed an approach that simplifies the generation and …

Acute gastroenteritis is one of the most common diseases in humans worldwide. Viruses are
recognized as important causes of this disease, particularly in children. Since the Norwalk …

The aim of this study was to investigate the influence of cell cycle on transfection efficiency.
Counterflow centrifugal elutriation was used which avoids possible side-effects from …

Adenoviruses have served as a model for investigating viral-cell interactions and
discovering different cellular processes, such as RNA splicing and DNA replication. In …

Candidate mammalian odorant receptors were first cloned some 6 years ago. The
physiological function of these receptors in initiating transduction in olfactory receptor …

The hdm2 gene is overexpressed in a variety of human tumors. Its gene product localizes
predominantly to the nucleus, where it acts as an inhibitor of the p53 tumor suppressor gene …

Two barriers prevent adenovirus-based vectors from having wide application. One is the
difficulty of making new adenoviruses, and the second is the strong immunological reaction …