Targeting mitochondria with ClpP agonists as a novel therapeutic opportunity in breast cancer
R Wedam, YE Greer, DJ Wisniewski, S Weltz, M Kundu… - Cancers, 2023 - mdpi.com
Simple Summary Mitochondria, often called “the powerhouse of the cell”, generate most of
the energy required for all cellular processes. Mitochondria also provide a platform for …
the energy required for all cellular processes. Mitochondria also provide a platform for …
Nuclear isoform of RAPH1 interacts with FOXQ1 to promote aggressiveness and radioresistance in breast cancer
Q Liu, Y Cao, X Wei, H Dong, M Cui, S Guan… - Cell Death & …, 2023 - nature.com
Radioresistance limits the efficacy of radiotherapy against breast cancer, especially the most
lethal subtype of breast cancer, triple-negative breast cancer (TNBC). Epithelial-to …
lethal subtype of breast cancer, triple-negative breast cancer (TNBC). Epithelial-to …
BUB1 Inhibition Sensitizes TNBC Cell Lines to Chemotherapy and Radiotherapy
Simple Summary An inhibitor of BUB1 increases the cytotoxic ability of different classes of
chemotherapy, targeted agents, and radiotherapy in triple-negative breast cancer, which is …
chemotherapy, targeted agents, and radiotherapy in triple-negative breast cancer, which is …
[PDF][PDF] Targeting mitochondria with CLPP agonists as a novel therapeutic opportunity in breast cancer. Cancers, 2023, 15, 1936
R Wedam, YE Greer, DJ Wisniewski, S Weltz, M Kundu… - 2023 - academia.edu
Breast cancer is the most frequently diagnosed malignancy worldwide and the leading
cause of cancer mortality in women. Despite the recent development of new therapeutics …
cause of cancer mortality in women. Despite the recent development of new therapeutics …
Investigating radiation therapy treatments with cell cycle and DNA repair inhibitors in triple-negative breast cancer
YC Tsai - 2024 - escholarship.mcgill.ca
Triple-negative breast cancers (TNBCs) are the most aggressive and the deadliest of all
breast cancer molecular subtypes. Patients with TNBCs have limited treatment options and …
breast cancer molecular subtypes. Patients with TNBCs have limited treatment options and …
Apoptosis induction in breast cancer cells after radiotherapy and potential radiosensitizers
K Simonsson - 2023 - gupea.ub.gu.se
Background. Today breast cancer is the foremost cancer death type amongst women around
the world. At present some of the toughest challenges in the clinic is recurrent, radioresistant …
the world. At present some of the toughest challenges in the clinic is recurrent, radioresistant …
Nuclear isoform of RAPH1 interacts with FOXQ1 to promote progression and radioresistance in triple-negative breast cancer through the STAT3 pathway
P **ng, Q Liu, Y Cao, X Wei, H Dong, M Cui, S Guan… - 2023 - researchsquare.com
Radioresistance limits the efficacy of radiotherapy against triple-negative breast cancer
(TNBC). Epithelial-to-mesenchymal transition (EMT) is closely related to tumor …
(TNBC). Epithelial-to-mesenchymal transition (EMT) is closely related to tumor …