Accelerating antiviral drug discovery: lessons from COVID-19
During the coronavirus disease 2019 (COVID-19) pandemic, a wave of rapid and
collaborative drug discovery efforts took place in academia and industry, culminating in …
collaborative drug discovery efforts took place in academia and industry, culminating in …
Persistent SARS-CoV-2 infection, EBV, HHV-6 and other factors may contribute to inflammation and autoimmunity in long COVID
A Vojdani, E Vojdani, E Saidara, M Maes - Viruses, 2023 - mdpi.com
A novel syndrome called long-haul COVID or long COVID is increasingly recognized in a
significant percentage of individuals within a few months after infection with SARS-CoV-2 …
significant percentage of individuals within a few months after infection with SARS-CoV-2 …
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
(COVID-19) syndrome, but its underlying mechanisms are not completely understood …
Macrophage phenotypes and functions: resolving inflammation and restoring homeostasis
Inflammation must be tightly regulated to both defend against pathogens and restore tissue
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …
homeostasis. The resolution of inflammatory responses is a dynamic process orchestrated …
A persistent neutrophil-associated immune signature characterizes post–COVID-19 pulmonary sequelae
Interstitial lung disease and associated fibrosis occur in a proportion of individuals who have
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
recovered from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
Animal models of Long Covid: A hit-and-run disease
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic has caused
more than 7 million deaths globally. Despite the presence of infection-and vaccine-induced …
more than 7 million deaths globally. Despite the presence of infection-and vaccine-induced …
Mucosal vaccine-induced cross-reactive CD8+ T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection
A nasally delivered chimpanzee adenoviral-vectored severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) vaccine (ChAd-SARS-CoV-2-S) is currently used in India …
coronavirus 2 (SARS-CoV-2) vaccine (ChAd-SARS-CoV-2-S) is currently used in India …
Recruited atypical Ly6G+ macrophages license alveolar regeneration after lung injury
The lung is constantly exposed to airborne pathogens and particles that can cause alveolar
damage. Hence, appropriate repair responses are essential for gas exchange and life. Here …
damage. Hence, appropriate repair responses are essential for gas exchange and life. Here …
Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge
Abstract Ever-evolving SARS-CoV-2 variants of concern (VOCs) have diminished the
effectiveness of therapeutic antibodies and vaccines. Develo** a coronavirus vaccine that …
effectiveness of therapeutic antibodies and vaccines. Develo** a coronavirus vaccine that …
Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19
Postacute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection (PASC) represent an urgent public health challenge and are estimated to affect …
infection (PASC) represent an urgent public health challenge and are estimated to affect …