CAP superfamily proteins from venomous animals: Who we are and what to do?

Q Zhang, J Xu, X Zhou, Z Liu - International Journal of Biological …, 2022 - Elsevier
Cysteine-rich secretory proteins (CRISPs), antigen 5 (Ag5), and pathogenesis-related (PR-
1) superfamily proteins (CAP superfamily proteins) are found in diverse species across the …

French scorpionism (mainland and oversea territories): narrative review of scorpion species, scorpion venom, and envenoming management

JA Vaucel, S Larréché, C Paradis, A Courtois, JM Pujo… - Toxins, 2022 - mdpi.com
Sixty-seven scorpion species have been described in France and its territories, where they
have been found to be heterogeneously distributed. Indeed, only one species can be found …

The enzymatic core of scorpion venoms

G Delgado-Prudencio, JI Cid-Uribe, JA Morales… - Toxins, 2022 - mdpi.com
Enzymes are an integral part of animal venoms. Unlike snakes, in which enzymes play a
primary role in envenomation, in scorpions, their function appears to be ancillary in most …

Unveiling the Protein Components of the Secretory-Venom Gland and Venom of the Scorpion Centruroides possanii (Buthidae) through Omic Technologies

PE García-Villalvazo, JM Jiménez-Vargas… - Toxins, 2023 - mdpi.com
Centruroides possanii is a recently discovered species of “striped scorpion” found in Mexico.
Certain species of Centruroides are known to be toxic to mammals, leading to numerous …

Comparative Proteomic Analysis of the Venoms from the Most Dangerous Scorpions in Morocco: Androctonus mauritanicus and Buthus occitanus

I Hilal, S Khourcha, A Safi, A Hmyene, S Asnawi… - Life, 2023 - mdpi.com
Morocco is known to harbor two of the world's most dangerous scorpion species: the black
Androctonus mauritanicus (Am) and the yellow Buthus occitanus (Bo), responsible for 83 …

Transcriptomic and proteomic analyses of venom glands from scorpions Liocheles australasiae, Mesobuthus martensii, and Scorpio maurus palmatus

WL So, TCN Leung, W Nong, WG Bendena, SM Ngai… - Peptides, 2021 - Elsevier
Scorpion venom contains a cocktail of differing peptides and proteins. Previous studies
focused on the identification of species-specific components in scorpion venoms, and …

The remarkably enzyme-rich venom of the Big Bend Scorpion (Diplocentrus whitei)

GS Nystrom, SA Ellsworth, DR Rokyta - Toxicon, 2023 - Elsevier
Scorpion venoms have long been studied for their peptide discovery potential, with modern
high-throughput venom-characterization techniques paving the way for the discovery of …

Beta-KTx14. 3, a scorpion toxin, blocks the human potassium channel KCNQ1

G Titaux-Delgado, AE Lopez-Giraldo, E Carrillo… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Potassium channels play a key role in regulating many physiological processes, thus,
alterations in their proper functioning can lead to the development of several diseases …

[HTML][HTML] Toxinology in the proteomics era: a review on arachnid venom proteomics

FC Marchi, E Mendes-Silva… - Journal of venomous …, 2022 - SciELO Brasil
The word venomics was coined to acknowledge the studies that use omics to investigate
venom proteins and peptides. Venomics has evolved considerably over the last 20 years …

[HTML][HTML] Optimizing Scorpion Toxin Processing through Artificial Intelligence

A Psenicnik, AA Ojanguren-Affilastro, MR Graham… - Toxins, 2024 - mdpi.com
Scorpion toxins are relatively short cyclic peptides (< 150 amino acids) that can disrupt the
opening/closing mechanisms in cell ion channels. These peptides are widely studied for …