Antibiotic resistance is one of the greatest contemporary threats to the human health, which
has increasingly been undermining the effectiveness of existing antimicrobial therapies …

Nitroaromatic compounds (ArNO2) maintain their importance in relation to industrial
processes, environmental pollution, and pharmaceutical application. The manifestation of …

Nitroreductases, present within both prokaryotes and eukaryotes, form a group of flavin‐
dependent enzymes capable of reducing nitro compounds using NAD (P) H as reducing …

Methicillin-resistant Staphylococcus aureus (MRSA) is the most common and widespread
antibiotic-resistant species. Novel Schiff-bases (2–8) have been synthesized and …

Nano zero-valent iron (nZVI) can enhance pollutants biodegradation, but it displays toxicity
towards microorganisms. Gram-positive (G+) bacteria exhibit greater resistance to nZVI than …

Background Antimicrobial combinations have been proven as a promising approach in the
confrontation with multi-drug resistant bacterial pathogens. In the present study, we identify …

Aims: Epidemiological investigations have indicated low resistance toward nitrofuran in
clinical isolates, suggesting its potential application in the treatment of multidrug-resistant …

We designed, synthesized, and tested twenty-six novel tetrahydroisoquinoline
carbohydrazide compounds for their anti-mycobacterial activity. Utilizing mass spectrometry …

The use of antibiotics has led to the emergence of multidrug-resistant (MDR) bacteria, and
there is an urgent need to find alternative treatments to alleviate this pressure. The type VI …

The combined application of furazolidone and vancomycin has previously been shown to be
synergistic against Gram-negative pathogens, with great therapeutic promise. However, the …