[HTML][HTML] COVID-19: the inflammation link and the role of nutrition in potential mitigation

I Zabetakis, R Lordan, C Norton, A Tsoupras - Nutrients, 2020 - mdpi.com
The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 …

Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents

R Lordan, A Tsoupras, I Zabetakis - Blood reviews, 2021 - Elsevier
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives

R Lordan, A Tsoupras, I Zabetakis, CA Demopoulos - Molecules, 2019 - mdpi.com
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …

Traumatic inflammatory response: pathophysiological role and clinical value of cytokines

R Li, JJ Ye, L Gan, M Zhang, D Sun, Y Li… - European Journal of …, 2024 - Springer
Severe trauma is an intractable problem in healthcare. Patients have a widespread immune
system response that is complex and vital to survival. Excessive inflammatory response is …

The multifaceted effects of non-steroidal and non-opioid anti-inflammatory and analgesic drugs on platelets: current knowledge, limitations, and future perspectives

A Tsoupras, DA Gkika, I Siadimas… - Pharmaceuticals, 2024 - mdpi.com
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most widely utilized
pharmaceuticals worldwide. Besides their recognized anti-inflammatory effects, these drugs …

Effects of omega-3 polyunsaturated fatty acids and their metabolites on haemostasis—current perspectives in cardiovascular disease

J Golanski, P Szymanska, M Rozalski - International journal of molecular …, 2021 - mdpi.com
The beneficial effects of long-chain polyunsaturated omega-3 fatty acids (omega-3 PUFAs)
in cardioprotection are widely known and generally accepted. In this literature review, we …

[HTML][HTML] A Review on Apple Pomace Bioactives for Natural Functional Food and Cosmetic Products with Therapeutic Health-Promoting Properties

M Vandorou, C Plakidis, IM Tsompanidou… - International journal of …, 2024 - mdpi.com
Apples are consumed lavishly worldwide, while demand is increasing for the management
of the huge apple-waste amounts that lead to significant disposal costs and ecological …

Nutritional Benefits of Bioactive Compounds from Watermelon: A Comprehensive Review

P Meghwar, SMG Saeed, A Ullah, E Nikolakakis… - Food Bioscience, 2024 - Elsevier
Valorization of agricultural byproducts has attained the consumer's interest because of the
numerous health benefits of bioactive. Watermelon (Citrullus lanatus) and its byproducts are …

Thrombosis and COVID-19: The Potential role of nutrition

A Tsoupras, R Lordan, I Zabetakis - Frontiers in Nutrition, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the
coronavirus disease (COVID-19), is a contagion that has rapidly spread around the globe …

Cardio-protective properties and health benefits of fish lipid bioactives; the effects of thermal processing

A Tsoupras, C Brummell, C Kealy, K Vitkaitis… - Marine Drugs, 2022 - mdpi.com
The beneficial effects of fish-derived lipid bioactives have come to prominence over the last
few decades, especially for their utilization in fish oils, supplements, and nutraceuticals …