Oxidative stress in ageing and chronic degenerative pathologies: molecular mechanisms involved in counteracting oxidative stress and chronic inflammation

TS Leyane, SW Jere, NN Houreld - International journal of molecular …, 2022‏ - mdpi.com
Ageing and chronic degenerative pathologies demonstrate the shared characteristics of
high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent …

Regenerative stem cell therapy for neurodegenerative diseases: an overview

F Sivandzade, L Cucullo - International journal of molecular sciences, 2021‏ - mdpi.com
Neurodegenerative diseases resulting from the progressive loss of structure and/or function
of neurons contribute to different paralysis degrees and loss of cognition and sensation. The …

The potential use of mesenchymal stem cells and their exosomes in Parkinson's disease treatment

RM Heris, M Shirvaliloo, S Abbaspour-Aghdam… - Stem Cell Research & …, 2022‏ - Springer
Parkinson's disease (PD) is the second most predominant neurodegenerative disease
worldwide. It is recognized clinically by severe complications in motor function caused by …

[HTML][HTML] The stem cell secretome and its role in brain repair

D Drago, C Cossetti, N Iraci, E Gaude, G Musco… - Biochimie, 2013‏ - Elsevier
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …

Current progress in the derivation and therapeutic application of neural stem cells

Y Tang, P Yu, L Cheng - Cell death & disease, 2017‏ - nature.com
Neural stem cells (NSCs) have a unique role in neural regeneration. Cell therapy based on
NSC transplantation is a promising tool for the treatment of nervous system diseases …

Stem cell‐based cell therapy in neurological diseases: a review

SU Kim, J De Vellis - Journal of neuroscience research, 2009‏ - Wiley Online Library
Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …

Targeted delivery of neural stem cells to the brain using MRI-guided focused ultrasound to disrupt the blood-brain barrier

A Burgess, CA Ayala-Grosso, M Ganguly, JF Jordao… - PloS one, 2011‏ - journals.plos.org
Stem cell therapy is a promising strategy to treat neurodegenerative diseases, traumatic
brain injury, and stroke. For stem cells to progress towards clinical use, the risks associated …

Neural stem cell–mediated enzyme/prodrug therapy for glioma: Preclinical studies

KS Aboody, J Najbauer, MZ Metz, M D'Apuzzo… - Science translational …, 2013‏ - science.org
High-grade gliomas are extremely difficult to treat because they are invasive and therefore
not curable by surgical resection; the toxicity of current chemo-and radiation therapies limits …

Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells

G Martino, S Pluchino, L Bonfanti… - Physiological …, 2011‏ - journals.physiology.org
Regenerative processes occurring under physiological (maintenance) and pathological
(reparative) conditions are a fundamental part of life and vary greatly among different …

Neural stem cell‐based treatment for neurodegenerative diseases

SU Kim, HJ Lee, YB Kim - Neuropathology, 2013‏ - Wiley Online Library
Human neurodegenrative diseases such as P arkinson's disease (PD), H untington's
disease (HD), amyotrophic lateral sclerosis (ALS) and A lzheimer's disease (AD) are caused …