Flavonoids are a group of polyphenolic compounds, diverse in chemical structure and
characteristics, found ubiquitously in plants. Therefore, flavonoids are part of the human diet …

The compositions of lesion types that precede and that may initiate the development of
advanced atherosclerotic lesions are described and the possible mechanisms of their …

Evidence to support an important role of oxidative modification in mediating the
atherogenicity of LDL continues to grow. New hypotheses suggest mechanisms by which Ox …

The purpose of this study is to provide a comprehensive survey on the compositional
properties of LDL (eg, lipid classes, fatty acids, antioxidants) relevant for its susceptibility to …

The clinical events resulting from atherosclerosis are directly related to the oxidation of lipids
in LDLs that become trapped in the extracellular matrix of the subendothelial space. These …

Chance and serendipity play major roles in the history of science. Too often, though, their
contributions do not show up in formal publications. We all tend to shape history according …

Over the last few decades, colloidal drug delivery systems (CDDS) such as nano-structures
have been developed in order to improve the efficiency and the specificity of drug action …

Caveolae or noncoated plasmalemmal vesicles found in a variety of cells have been
implicated in a number of important cellular functions including endocytosis, transcytosis …

Evolution of plaque that is prone to rupture is characterized by inflammation and physical
changes. Accumulation of low-density lipoprotein in the sub-intima provides esterified …

Three lines of evidence are presented that low density lipoproteins gently extracted from
human and rabbit atherosclerotic lesions (lesion LDL) greatly resembles LDL that has been …