Five-membered heterocycles are essential structural components in various antibacterial
drugs; the physicochemical properties of a five-membered heterocycle can play a crucial …

Due to the long-term and widespread use of antibiotics in clinic, the problem of bacterial
resistance is increasingly serious, and the development of new drugs to treat drug-resistant …

Tuberculosis is today amongst the worldwide health threats. As resistant strains of
Mycobacterium tuberculosis have slowly emerged, treatment failure is too often a fact …

Protein synthesis is one of the major targets in the cell for antibiotics. This review endeavors
to provide a comprehensive “post-ribosome structure” A–Z of the huge diversity of antibiotics …

The widespread use of antibiotics has made the problem of bacterial resistance increasingly
serious, and the study of new drug-resistant bacteria has become the main direction of …

Using a continuous flow reactor, the dehydration of D-fructose and other carbohydrates to 5-
(chloromethyl) furfural (1) is achieved in reaction times as short as 60 s. The biphasic flow …

The increasing drug resistance of M ycobacterium tuberculosis to the currently used drugs
and HIV coinfection has caused alarm in the international scientific community …

This review provides a comprehensive survey of proprietary drug discovery and
development efforts performed by Indian companies between 1994 and mid‐2016. It is …

Abstract 2-[6-(Morpholin-4-yl) pyridin-3-ylamino] acetohydrazide (4) was obtained starting
from 6-morpholin-4-ylpyridin-3-amine (2) via the formation of ester (3) and then converted to …

Infectious diseases caused by bacterial pathogens are a leading cause of mortality
worldwide. In particular, recalcitrant bacterial communities known as biofilms are implicated …