Effect of saffron, black seed, and their main constituents on inflammatory cytokine response (mainly TNF-α) and oxidative stress status: An aspect on pharmacological …

Z Vafaeipour, M Ghasemzadeh Rahbardar… - Naunyn-Schmiedeberg's …, 2023 - Springer
Tumor necrosis factor-α (TNF-α), an inflammatory cytokine, is produced by monocytes and
macrophages. It is known as a'double-edged sword'because it is responsible for …

Chrysin mitigates diclofenac-induced hepatotoxicity by modulating oxidative stress, apoptosis, autophagy and endoplasmic reticulum stress in rats

B Varışlı, C Caglayan, FM Kandemir, C Gür… - Molecular Biology …, 2023 - Springer
Background Diclofenac (DF) is a non-steroidal anti-inflammatory drug (NSAID) generally
prescribed for the treatment of pain. In spite of the widespread use of DF, hepatotoxicity has …

[HTML][HTML] Lycopene corrects metabolic syndrome and liver injury induced by high fat diet in obese rats through antioxidant, anti-inflammatory, antifibrotic pathways

T Albrahim, MA Alonazi - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Obesity is a global epidemic disease that is closely associated with various health problems
as Diabetes mellitus, cardiovascular, and metabolic disorders. Lycopene (LYC), a red …

[HTML][HTML] Liquiritigenin protects against arsenic trioxide-induced liver injury by inhibiting oxidative stress and enhancing mTOR-mediated autophagy

M Zhang, Y Xue, B Zheng, L Li, X Chu, Y Zhao… - Biomedicine & …, 2021 - Elsevier
Liquiritigenin (LQ) has protective effects against various hepatotoxicities. However, its
specific role on arsenic trioxide (ATO)-induced hepatotoxicity and the related biomolecular …

Silver nanoparticles enhance oxidative stress, inflammation, and apoptosis in liver and kidney tissues: potential protective role of thymoquinone

B Salama, KJ Alzahrani, KS Alghamdi… - Biological trace element …, 2023 - Springer
Silver nanoparticles (AgNPs) are the most common nanomaterials in consumer products.
Therefore, it has been crucial to control AgNPs toxicological effects to improve their safety …

Protocatechuic acid abrogates oxidative insults, inflammation, and apoptosis in liver and kidney associated with monosodium glutamate intoxication in rats

RB Kassab, A Theyab, AO Al-Ghamdy… - … Science and Pollution …, 2022 - Springer
Monosodium glutamate (MSG), a commonly used flavor enhancer, has been reported to
induce hepatic and renal dysfunctions. In this study, the palliative role of protocatechuic acid …

Protective potential of thymoquinone against cadmium, arsenic, and lead toxicity: A short review with emphasis on oxidative pathways

F Ghasemi, A Nili‐Ahmadabadi… - Journal of Applied …, 2023 - Wiley Online Library
Heavy metals are among the most important environmental pollutions used in various
industries. Their extensive use has increased human susceptibility to different chronic …

Ameliorative effect of thymoquinone and thymoquinone nanoparticles against diazinon-induced hepatic injury in rats: A possible protection mechanism

WM Nassar, WM El-Kholy, MR El-Sawi, NM El-Shafai… - Toxics, 2023 - mdpi.com
The health benefits of thymoquinone (TQ) have been a significant focus of numerous
studies. However, more research is needed to ascertain whether its nano-form can …

Therapeutic effects of thymoquinone in doxorubicin‐induced hepatotoxicity via oxidative stress, inflammation and apoptosis

AT Akin, E Öztürk, E Kaymak… - Anatomia, histologia …, 2021 - Wiley Online Library
Cancer is a lethal disease that is characterized by uncontrolled cell division and
proliferation, and it results in death in many organisms. Doxorubicin (DOX) is a therapeutic …

Antioxidative and energy metabolism-improving effects of maca polysaccharide on cyclophosphamide-induced hepatotoxicity mice via metabolomic analysis and …

W Fei, J Zhang, S Yu, N Yue, D Ye, Y Zhu, R Tao… - Nutrients, 2022 - mdpi.com
Lepidium meyenii Walp.(Maca), as a natural food supplement, has strong antioxidant and
energy metabolism-improving characteristics, and Maca polysaccharide (MP) is its effective …