Brown spiders and loxoscelism

PH Da Silva, RB Da Silveira, MH Appel, OC Mangili… - Toxicon, 2004 - Elsevier
Accidents caused by brown spiders (Loxosceles genus) are classically associated with
dermonecrotic lesions and systemic manifestations including intravascular haemolysis …

Antivenom treatment in arachnidism: antivenoms

GK Isbister, A Graudins, J White… - Journal of Toxicology …, 2003 - Taylor & Francis
Envenomation by arachnids causes significant medical illness worldwide. Scorpion sting is
the most important arachnid envenomation causing adult morbidity and pediatric mortality …

Enzymatic characterization, antigenic cross-reactivity and neutralization of dermonecrotic activity of five Loxosceles spider venoms of medical importance in the …

KC Barbaro, I Knysak, R Martins, C Hogan, K Winkel - Toxicon, 2005 - Elsevier
Loxosceles spiders have a wide distribution in the temperate and tropical regions of the
world. Loxoscelism is characterized by necrotic skin ulceration at the bite site and, less …

Forty years of the description of brown spider venom phospholipases-D

LH Gremski, HC Da Justa, TP Da Silva, NLC Polli… - Toxins, 2020 - mdpi.com
Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a
serious public health issue, especially in regions of hot or temperate climates, such as parts …

[HTML][HTML] Highlights in the knowledge of brown spider toxins

D Chaves-Moreira, A Senff-Ribeiro… - Journal of Venomous …, 2017 - SciELO Brasil
Brown spiders are venomous arthropods that use their venom for predation and defense. In
humans, bites of these animals provoke injuries including dermonecrosis with gravitational …

Identification of high molecular weight serine-proteases in Loxosceles intermedia (brown spider) venom

SS Veiga, RB da Silveira, JL Dreyfuss, J Haoach… - Toxicon, 2000 - Elsevier
High molecular weight serine-proteases have been identified in Loxosceles intermedia
(brown spider) venom. The mechanism by which Loxosceles spp venoms cause …

Molecular cloning and functional characterization of two isoforms of dermonecrotic toxin from Loxosceles intermedia (brown spider) venom gland

RB da Silveira, RB Pigozzo, OM Chaim, MH Appel… - Biochimie, 2006 - Elsevier
Brown spider (Genus Loxosceles) bites are normally associated with necrotic skin
degeneration, gravitational spreading, massive inflammatory response at injured region …

The efficacy of antivenom in loxoscelism treatment

I Pauli, J Puka, IC Gubert, JC Minozzo - Toxicon, 2006 - Elsevier
Loxoscelism or brown spider envenomation is the most important form of araneism in some
countries and constitutes the third cause of accidents by venomous animals in Brazil. The …

Morphological and biochemical evidence of blood vessel damage and fibrinogenolysis triggered by brown spider venom

VC Zanetti, RB Da Silveira, JL Dreyfuss… - Blood coagulation & …, 2002 - journals.lww.com
The venom of the brown spider is remarkable because it causes dermonecrotic injury,
hemorrhagic problems, hemolysis, platelet aggregation and renal failure. The mechanism by …

Context‐dependent venom deployment and protein composition in two assassin bugs

ML Fischer, N Wielsch, DG Heckel… - Ecology and …, 2020 - Wiley Online Library
The Heteroptera are a diverse suborder of phytophagous, hematophagous, and
zoophagous insects. The shift to zoophagy can be traced back to the transformation of …