Evolution of RNA viruses occurs through disequilibria of collections of closely related mutant
spectra or mutant clouds termed viral quasispecies. Here we review the origin of the …

The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

Viral quasispecies refers to a population structure that consists of extremely large numbers
of variant genomes, termed mutant spectra, mutant swarms or mutant clouds. Fueled by high …

Deformed wing virus (DWV; Iflaviridae) is one of many viruses infecting honeybees and one
of the most heavily investigated due to its close association with honeybee colony collapse …

During viral infections, the complex and dynamic distributions of variants, termed viral
quasispecies, play a key role in the adaptability of viruses to changing environments and the …

Quasispecies dynamics mediates adaptability of RNA viruses through a number of
mechanisms reviewed in the present article, with emphasis on the medical implications for …

Abstract Information concepts from physics, mathematics and computer science support
many areas of research in biology. Their focus is on objective information, which provides …

Experimental evidence that RNA virus populations consist of distributions of mutant
genomes, termed quasispecies, was first published 31 years ago. This work provided the …

Continuous genetic variation and selection of virus subpopulations in the course of RNA
virus replications are intimately related to viral disease mechanisms. The central topics of …

Selection of inhibitor-resistant viral mutants is universal for viruses that display quasi-
species dynamics, and hepatitis C virus (HCV) is no exception. Here we review recent …